Results 191 to 200 of about 1,815,900 (374)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Comparative Analyses of Cyanoacrylates for Barrier Protection and Incontinence-Related Wash-Off Resistance. [PDF]

Int Wound J
Pradhan MA, Nicholson LM, Coles LS, Campbell JJ, Curtis BJ.   +4 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

CANDID-CNS: AI Unlocks Stereochemistry and Beyond Rule of 5 to Predict CNS Penetration of Small Molecules. [PDF]

J Chem Inf Model
Collins JW, Abedi M, Ramirez D, Philippe-Venec L, Moore B, Asher JO.   +5 more
europepmc   +1 more source

Improving Webserver Security for Local Tax Reporting Applications Using Standard Penetration Testing Execution Methods

, 2020
Yosua Ade Pohan, Yuhandri Yunus, S Sumijan   +2 more
openalex   +1 more source

Energy measurement in the standard penetration test [PDF]

, 1981
William D Kovacs, Lawrence A salamone, Felix Y Yokel   +2 more
openaire   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Polydopamine-Functionalized Zinc Oxide Nanoparticles as a Root Canal Sealer: Characterization, Biological, and Physicochemical Properties. [PDF]

Bioinorg Chem Appl
Raj AN, Shetty A, Rao LN.
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Finite element analysis and in vitro simulation experiments on ophthalmic trocar needles. [PDF]

Front Bioeng Biotechnol
Sun J, Zhang Z, Yuan H, Zhao G.
europepmc   +1 more source