Results 51 to 60 of about 10,171,563 (247)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Advances in Civil Engineering, 2019 Taking the project of the Su-xin highway treated by using the resonant compaction method as the reference, a new method for the evaluation of liquefaction potential is proposed based on the piezocone penetration test (CPTU) and the standard penetration ...
Guangyin Du +4 more
doaj +1 more source
An investigation of correlation factors linking footing resistance on sand with cone penetration test results [PDF]
, 2012 Significant research effort has led to improvements in our ability to estimate the ultimate bearing resistance of footings in sand. These techniques often estimate the footing resistance at relatively large displacements, typically 10% of the footing ...
Gavin, Kenneth, Tolooiyan, Ali
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Discover Civil EngineeringThis study aims to quantitatively evaluate soil and rock penetration characteristics and subsurface heterogeneity within the crystalline basement terrain of the Lower Thamirabarani River Basin, southern India, through integrated geophysical and ...
S. Richard Abishek +6 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Journal of Engineering, 2011 In this research the relation between skin resistances and standard penetration test of over consolidated clay soils has been studied. The research includes doing boreholes at Babil governorate in Iraq to get undisturbed samples and standard penetration
Zuhair Kadhim Jahan Ger
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source