Results 61 to 70 of about 208,631 (258)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Düzce İli Camikebir Mahallesi Kentsel Dönüşüm Alanı Zeminlerinin Sıvılaşma Potansiyelinin Arazi Deneyleri İle Araştırılması

open access: yesDüzce Üniversitesi Bilim ve Teknoloji Dergisi, 2014
Bu çalışma, Düzce ili Camikebir Mahalllesinde kentsel dönüşüm alanında alüvyal zeminlerin olası bir deprem etkisinde sıvılaşma potansiyelinin, arazi (SPT) verileri kullanılarak belirlenmesini içermektedir.
Ali ATEŞ
doaj   +6 more sources

Comparing nonlinear regression analysis and ‎artificial neural networks to predict geotechnical ‎parameters from standard penetration test [PDF]

open access: yesUrbanism. Arhitectura. Constructii, 2018
At the beginning the twenty-first century, a lot of high-level methods have become ‎available in geotechnical engineering in order to deal with the complexity and ‎heterogeneity encountered in soil, Statistical modeling (i.e. regression analysis method) ‎
Mohammed Amin‎ Benbouras   +4 more
doaj  

STUDI KORELASI EMPIRIS ANTARA NILAI TAHANAN STANDARD PENETRATION TEST (N SPT) DENGAN KEKUATAN GESER UNDRAINED (Su) TANAH KOHESIF KOTA CILEGON

open access: yesTeknika, 2014
Pengujian tanah di lapangan dengan menggunakan Standard Penetration Test (SPT) umum digunakan untuk mengetahui kekuatan tanah. Beberapan korelasi antara nilai N SPT dengan parameter kekuatan tanah telah banyak dikembangkan di beberapa negara berbeda ...
Enden Mina, Rama Indera Kusuma
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Assessing liquefaction potential in Dhaka: a case study of some reclaimed lands using LPI and Monte Carlo simulation

open access: yesSmart Construction and Sustainable Cities
Dhaka, the capital of Bangladesh, is one of the largest cities in the world. It is rapidly growing, and new housing areas are being developed by filling water bodies and flood-prone lowlands.
Mohammad Saiful Islam   +2 more
doaj   +1 more source

Standard Penetrasyon Deneyi (SPT) ile Düzce ili Darıcı Mahallesi Zemininin Sıvılaşma Potansiyelinin Araştırılması

open access: yesDüzce Üniversitesi Bilim ve Teknoloji Dergisi, 2014
Bu çalışma, Düzce ili Darıcı Mahallesi yerleşim alanında yapılması planlanan iki katlı yapı alanında mevcut olan alüvyal zeminlerin olası bir deprem etkisinde sıvılaşma potansiyelinin, arazi Standart Penetrasyon Testi (SPT) verileri kullanılarak ...
Ali ATEŞ, Burak YEŞİL
doaj   +6 more sources

Early‐Phase Research in Pediatric Neuro‐Oncology

open access: yes
Pediatric Blood &Cancer, EarlyView.
Jonathan Cunningham
wiley   +1 more source

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