Results 61 to 70 of about 208,631 (258)
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Bu çalışma, Düzce ili Camikebir Mahalllesinde kentsel dönüşüm alanında alüvyal zeminlerin olası bir deprem etkisinde sıvılaşma potansiyelinin, arazi (SPT) verileri kullanılarak belirlenmesini içermektedir.
Ali ATEŞ
doaj +6 more sources
Comparing nonlinear regression analysis and artificial neural networks to predict geotechnical parameters from standard penetration test [PDF]
At the beginning the twenty-first century, a lot of high-level methods have become available in geotechnical engineering in order to deal with the complexity and heterogeneity encountered in soil, Statistical modeling (i.e. regression analysis method)
Mohammed Amin Benbouras +4 more
doaj
Pengujian tanah di lapangan dengan menggunakan Standard Penetration Test (SPT) umum digunakan untuk mengetahui kekuatan tanah. Beberapan korelasi antara nilai N SPT dengan parameter kekuatan tanah telah banyak dikembangkan di beberapa negara berbeda ...
Enden Mina, Rama Indera Kusuma
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Dhaka, the capital of Bangladesh, is one of the largest cities in the world. It is rapidly growing, and new housing areas are being developed by filling water bodies and flood-prone lowlands.
Mohammad Saiful Islam +2 more
doaj +1 more source
Bu çalışma, Düzce ili Darıcı Mahallesi yerleşim alanında yapılması planlanan iki katlı yapı alanında mevcut olan alüvyal zeminlerin olası bir deprem etkisinde sıvılaşma potansiyelinin, arazi Standart Penetrasyon Testi (SPT) verileri kullanılarak ...
Ali ATEŞ, Burak YEŞİL
doaj +6 more sources
Early‐Phase Research in Pediatric Neuro‐Oncology
Pediatric Blood &Cancer, EarlyView.
Jonathan Cunningham
wiley +1 more source

