Results 81 to 90 of about 10,171,563 (247)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Smart Construction and Sustainable CitiesDhaka, the capital of Bangladesh, is one of the largest cities in the world. It is rapidly growing, and new housing areas are being developed by filling water bodies and flood-prone lowlands.
Mohammad Saiful Islam +2 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2014 Bu çalışma, Düzce ili Darıcı Mahallesi yerleşim alanında yapılması planlanan iki katlı yapı alanında mevcut olan alüvyal zeminlerin olası bir deprem etkisinde sıvılaşma potansiyelinin, arazi Standart Penetrasyon Testi (SPT) verileri kullanılarak ...
Ali ATEŞ, Burak YEŞİL
doaj +6 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
, 1970 A Tractor and the testweight frame ready before a SIDE IMPACT TEST. The tractor is lashed down and the impacting weight is raised. The test was conducted at Mead, NE (Ag Eaxperiment Station) It was found that these "dynamic" tests were difficult to make ...
Nebraska Tractor Test Laboratory
core +3 more sources
CPT- and SPT-based probabilistic liquefaction assessment using adaptive kernel density estimation
KSCE Journal of Civil EngineeringThis study introduces a simplified stress-based model that enables quick assessment of the probability of liquefaction (PL) and post-liquefaction volumetric strain (εvol).
Javad Sadoghi Yazdi +2 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
GeoScience Engineering, 2018 The subsurface of a proposed site for building development in Mowe, Nigeria, using Standard Penetration Test (SPT), Cone Penetrometer Test (CPT) and Horizontal Electrical Profiling (HEP), was investigated with the aim of evaluating the suitability of the
Oyedele Kayode F. +2 more
doaj +1 more source
Penetration of fastener projectiles into construction materials [PDF]
, 1988 The normal impact, penetration of both projectile and fastener into soils, rocks, and concrete at low velocities has been investigated using theoretical, experimental, and numerical approaches under axisymmetric conditions.
Zhou, Gang
core