Results 161 to 170 of about 666,866 (314)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Fatigue in Dental Ceramics: A Call for Standardized Testing and Emerging Manufacturing Technologies. [PDF]

Materials (Basel)
Pereira GKR, Pilecco RO, Tribst JPM.
europepmc   +1 more source

Breast Cancer Detection: The Development and Pilot Study of a "Tactile Landscape" as a Standardized Testing Tool. [PDF]

Simul Healthc, 2019
Veitch DE, Bochner M, Molenbroek JFM, Goossens RHM, Owen H.   +4 more
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

New State Laws Reflect the Rethinking of Excessive Mandated Standardized Testing in America\u27s Public Schools

, 2015
The largest standardized testing cheating scandal in American history has caused many to question the practice of excessive standardized testing in America’s public education system.
DuBose, Renalia Smith
core  

Investigating the Integration of Student Learning Resources in Preparation for the NCLEX-RN: Phase One of a Canadian Two-Phase Multi-Site Study

Quality Advancement in Nursing Education, 2016
Shelley L Cobbett, Willena I Nemeth, JoAnne MacDonald   +2 more
doaj   +1 more source

References values and standardized testing protocols for performance-based and patient-reported outcome measures among individuals with lower limb amputation. [PDF]

Front Rehabil Sci
McGuire M, Nataletti S, Maronati R, Hoppe-Ludwig S, Banerjee A, Wacek A, Cave J, Looft JM, Dearth CL, Hendershot BD, Jayaraman A.   +10 more
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Standardized Testing Methods: Challenging the Traditional Structure of Evaluation

, 2017
Education is a route through which knowledge is acquired through training and then applied with intelligence, thinking and experience. Standardized testing in the field of education is a testing method safeguarding consistent conditions, scoring rules ...
, Foram Gathia, Janhavi Pawar
core  

Proposal of a standardized testing protocol for BPPV: Using 3D simulations for insights into movement of otoliths during positional tests. [PDF]

Eur Arch Otorhinolaryngol
Bhandari R, Bhandari A, Zee DS, Nuti D, Kingma H, van de Berg R.   +5 more
europepmc   +1 more source