Results 171 to 180 of about 666,866 (314)

A large animal model for standardized testing of bone regeneration strategies. [PDF]

BMC Vet Res, 2018
Ferguson JC, Tangl S, Barnewitz D, Genzel A, Heimel P, Hruschka V, Redl H, Nau T.   +7 more
europepmc   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

STAGER checklist: Standardized testing and assessment guidelines for evaluating generative artificial intelligence reliability. [PDF]

IMetaOmics
Chen J, Zhu L, Mou W, Lin A, Zeng D, Qi C, Liu Z, Jiang A, Tang B, Shi W, Kahlert UD, Zhou J, Guo S, Lu X, Sun X, Ngo T, Pu Z, Jia B, Jeon CO, He Y, Wu H, Gu S, Cheungpasitporn W, Huang H, Mao W, Wang S, Chen X, Cabannes L, Ren GSG, Whitaker IS, Ali S, Cheng Q, Miao K, Yuan S, Luo P.   +34 more
europepmc   +1 more source

A primer on standardized testing: History, measurement, classical test theory, item response theory, and equating. [PDF]

J Chiropr Educ, 2019
Himelfarb I.
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Range of Motion and Neutral Zone of All Human Spinal Motion Segments: A Data Collection of 30 Years of In Vitro Experiments Performed Under Standardized Testing Conditions. [PDF]

JOR Spine
Wilke HJ, Kienle A, Werner K, Liebsch C.
europepmc   +1 more source

Effects of group size on conversation treatment outcomes: Results of standardized testing. [PDF]

Aphasiology, 2018
Hoover EL, DeDe G, Maas E.
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Let the Seuss loose: limitations on standardized testing

, 2017
Modern education relies on standardized testing as a quantitative tool to validate the quality of education in the United States today. From as early as the 1800s standardized tests have been a part of the American fabric after they were first ...

core  

Standardized Testing for Thermal Evaluation of Bone Drilling: Towards Predictive Assessment of Thermal Trauma. [PDF]

Bioengineering (Basel)
Rugova S, Abboud M.
europepmc   +1 more source