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Teaching to the Test: A Controversial Issue in Quantitative Measurement [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2012
discussion of the pros and cons of focusing curricular and pedagogical decisions primarily on mastery of those skills and concepts measured by standardized tests. This paper presents scholarly discourse based on testing systems and school accountability,
Jennifer L. Styron, Ronald A. Styron
doaj  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Assessing authenticity in modelling test items: deriving a theoretical model

open access: yesFrontiers in Education
Authenticity is considered a central feature in the context of teaching and learning mathematical modelling and is often demanded for both learning tasks and test items.
Dominik Schlüter, Michael Besser
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

The achievement benefits of standardized testing

open access: yesNonpartisan Education Review, 2006
no ...
Richard P. Phelps
doaj  

AN INVESTIGATION INTO LEXICAL CONTENTS IN ENGLISH STANDARDIZED TESTS

open access: yesTạp chí Khoa học
This paper aims to critically analyze lexical contents in national English standardized tests in an EFL context. Using the Compleat Lexical Tutor corpus tool, the lexical profiles of these exams are meticulously examined, revealing the distribution of ...
Dinh Thi Mai Anh, Tran Ba Tien*
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Reassessing standardized tests: Evaluating their effectiveness in school performance measurement

open access: yesCurricula
This research article reassesses the role of standardized tests in educational assessment, focusing on their complexities, historical context, and implications. It examines the accountability, and academic achievement benchmarks these tests provide while
Oyeronke Christiana Paramole   +1 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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