Results 121 to 130 of about 1,661,930 (349)

A Comprehensive Approach to Facade Design for Preventing Rainwater Penetration: Implementation in Spanish Regions

open access: yesBuildings
Rainwater penetration into building facades results in multiple issues, including material and structural degradation, reduced energy efficiency, and health-related concerns among occupants.
José M. Pérez-Bella   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Confidence Intervals for Standardized Effect Sizes: Theory, Application, and Implementation [PDF]

open access: yes
The behavioral, educational, and social sciences are undergoing a paradigmatic shift in methodology, from disciplines that focus on the dichotomous outcome of null hypothesis significance tests to disciplines that report and interpret effect sizes and ...
Ken Kelley
core   +1 more source

Test Methods of Composite Materials [PDF]

open access: yes, 2008
Stručná příručka o normovaných zkouškách mechanických vlastností kompozitních materiálů zpevněných uhlíkovými, skleněnými a aramidovými vlákny. Práce obsahuje přehled nejdůležitějších normovaných zkoušek používaných v letectví a jejich stručný popis ...
Cieslar, Bogdan
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Teaching to the Test: A Controversial Issue in Quantitative Measurement [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2012
discussion of the pros and cons of focusing curricular and pedagogical decisions primarily on mastery of those skills and concepts measured by standardized tests. This paper presents scholarly discourse based on testing systems and school accountability,
Jennifer L. Styron, Ronald A. Styron
doaj  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Assessing authenticity in modelling test items: deriving a theoretical model

open access: yesFrontiers in Education
Authenticity is considered a central feature in the context of teaching and learning mathematical modelling and is often demanded for both learning tasks and test items.
Dominik Schlüter, Michael Besser
doaj   +1 more source

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