Results 61 to 70 of about 767,925 (267)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Unintended Consequences of using Tests to Improve Learning: How Improvement-Oriented Resources Heighten Conceptions of Assessment as School Accountability

Journal of MultiDisciplinary Evaluation, 2009
Over the past decade, the New Zealand government has created a set of resources to support teachers’ use of assessment for learning. These include Assessment Tools for Teaching and Learning (asTTle), a software program enabling teachers to create ...
Gavin T. L. Brown, Lois R. Harris
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Exploring standardized tests washback from the decolonial option: implications for rural teachers and students

Cogent Arts & Humanities
The lack of research from rural contexts evidences that coloniality is maintained not only in socioeconomics but also in education. Hence, this qualitative research synthesis explores the washback of English language standardized tests at the secondary ...
Yimmy Alexander Hoyos Pipicano
doaj   +1 more source

Are Standardized Tests Sensitive to Early Cognitive Change in Parkinson's Disease? [PDF]

Psychopharmacol Bull, 2023
Turner TH, Lench DH, Adams R, Wilson S, Marsicano C, Rodriguez-Porcel F.   +5 more
europepmc   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Beyond admission scores: evaluating GAT, SAAT, and English proficiency as predictors of physics performance in health science education

Frontiers in Medicine
BackgroundAccurate prediction of academic performance is essential for selecting students into competitive medical and health science programs. In Saudi Arabia, standardized cognitive assessments—such as the General Aptitude Test (GAT) and Scholastic ...
Abdulaziz Althewini
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Ecotoxicological Risk Assessment of Actellic 50 EC Insecticide on Non-Target Organisms in Parallel with the Application of Standardized Tests. [PDF]

Toxics, 2022
Paunescu A, Ponepal CM, Tofan L, Brinzea G, Tantu MM, Mihaescu CF, Draghiceanu OA, Popoviciu DR, Fagaras MM, Vasile D, Soare LC.   +10 more
europepmc   +1 more source