Results 81 to 90 of about 1,226,092 (307)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Does the Quality of Training Programs Matter? Evidence from Bidding Processes Data [PDF]
This paper estimates the effect of training quality on labor-market earnings using a Peruvian non-experimental training program, PROJOVEN, which targets disadvantaged youths aged 16 to 24 years. The identification of causal effects is possible because of
Alberto Chong, José Galdo
core
Reading Instruction for Students with Emotional Disturbance: A Mixed-Methods Investigation. [PDF]
, 2021 Although there is a substantial body of observation research investigating the manner in which reading instruction is provided to students with learning disabilities, there is little research in this area involving students with and at risk for emotional
Adamson, Reesha +2 more
core
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Clinical Diagnosis and Treatment of 31 Children with Mycoplasma pneumoniae Necrotizing Pneumonia
International Journal of General MedicineZhaoxia Wang,1 Yuxin Zhao,2 Hongfang Liu3 1Department of Pediatrics, Weihai Central Hospital Affiliated to Qingdao University, Weihai, Shandong, People’s Republic of China; 2Department of Ophthalmology, Weihai Central Hospital Affiliated to Qingdao ...
Wang Z, Zhao Y, Liu H
doaj
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Use of Standardized Assessments and Online Resources in Stroke Rehabilitation [PDF]
, 2019 Background: The extent to which movement-related standardized assessments and online resources are used in stroke rehabilitation is unclear in the United States.
Bosch, Pamela R +4 more
core +2 more sources
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Implementing Observation Protocols: Lessons for K-12 Education From the Field of Early Childhood [PDF]
, 2012 Examines issues for implementing standardized observation protocols for teacher evaluations. Makes recommendations based on lessons from preschool, such as the need to show empirical links between teacher performance and student learning and ...
Robert C. Pianta
core
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source