Results 101 to 110 of about 2,050,460 (296)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Evaluating the Leader’s Profile from the Team Members’ Perspective: A Case Study Applying Johari’s Window

open access: yesStandards
Leadership in an organizational environment is responsible for enabling team members to achieve their daily objectives. Leadership has evolved continuously over time, demonstrating flexibility as a core aspect of its essence. In an organizational setting,
Daniel Barbosa dos Santos Silva   +5 more
doaj   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Effective Practices for Implementing Quality Control Circles Aligned with ISO Quality Standards: Insights from Employees and Managers in the Food Industry

open access: yesStandards
Quality control circles (QCCs) are a proven method for fostering continuous improvement through employee involvement. However, the implementation process and organizational impact of QCCs in the food industry remain underexplored.
Ana Beatriz Silva de Lima   +5 more
doaj   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Effectiveness of YOLO Architectures in Tree Detection: Impact of Hyperparameter Tuning and SGD, Adam, and AdamW Optimizers

open access: yesStandards
This study investigates the optimization of tree detection in static images using YOLOv5, YOLOv8, and YOLOv11 models, leveraging a custom non-standard image bank created exclusively for this research.
André Magalhães Moraes   +5 more
doaj   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

Corporate Social Responsibility (CSR), Sustainability and ESG Standards Used by ATHEX ESG Index Listed Companies

open access: yesStandards
Corporate social responsibility (CSR) and sustainability have proliferated the corporate boardroom agenda and companies’ leadership teams are trying to find ways to improve their social and environmental performance and enhance their corporate governance
Triantafyllos Papafloratos   +1 more
doaj   +1 more source

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