Results 41 to 50 of about 244,591 (283)

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Radicalizing refamiliarization [PDF]

open access: yes, 2009
In this short article, our aim is to consider contemporary American visual culture through a contribution to the question concerning Barack Obama.
Armitage, John, Garnett, Joy
core   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Distribution des pratiques mégalithiques actuelles et subactuelles et dynamique du peuplement dans le Faro au nord du Cameroun durant ces deux derniers siècles

open access: yesAfriques
In the Faro Region, Northern Cameroon, megalithism appears on recent remains of modern villages and continues still today. But this heritage is still largely underexploited and threatened by destruction. The goal our study is first of all aims to analyze
Alice Lucie Mezop Temgoua-Noumissing
doaj   +1 more source

Cultures lithiques dans les monts Mandara au Cameroun

open access: yesAfrique Archéologie Arts, 2009
Research work carried out recently in the Mandara mountains in northern Cameroon enable us to appreciate the dynamism of its cultural stone heritage through the standing stones, rock art, mobile art and various stone structures.
Narcisse Santores Tchandeu
doaj   +1 more source

Lewis Coastal Chapel-Sites Survey: Topographic Survey 2005 [PDF]

open access: yes, 2006
This report describes the results of topographic surveys undertaken for the second year of the Lewis Coastal Chapel-sites Survey (LCCS) on four chapel-sites on the Isle of Lewis in 2005.
Barrowman, Rachel C, Hooper, Janet
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Squamous Cell Carcinoma of the Renal Pelvis as a Result of Long-Standing Staghorn Calculi

open access: yesCase Reports in Oncology, 2015
We report on a 79-year-old woman with staghorn calculi who presented with severe hypercalcemia. She was later found to have humoral hypercalcemia of malignancy caused by a rare tumor, squamous cell carcinoma of the renal pelvis.
Kamonchanok Jongyotha   +1 more
doaj   +1 more source

Character and the space of Clarel [PDF]

open access: yes, 2011
No description ...
Arac   +25 more
core   +2 more sources

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