Results 41 to 50 of about 12,724 (295)
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Not sucking in the seventies: The Rolling Stones and the myth of decline
, 2015 This article reappraises the Stones’ “lost years.” However, in covering their reputation-imperiling half-decade between 1973 and 1978, it reaches back to the band’s fabled 1960s heyday and forward to its “revival” in order to identify continuities in ...
Philo, S.
core +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Squamous Cell Carcinoma of the Renal Pelvis as a Result of Long-Standing Staghorn Calculi
Case Reports in Oncology, 2015 We report on a 79-year-old woman with staghorn calculi who presented with severe hypercalcemia. She was later found to have humoral hypercalcemia of malignancy caused by a rare tumor, squamous cell carcinoma of the renal pelvis.
Kamonchanok Jongyotha +1 more
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Gallia Préhistoire, 2018 The site of Kercado, in Carnac, is situated above the valley of Kerloquet and the ria that runs along the beach of Kerdual for 2 km. It comprises a probable low mound, the cairn of Mané er Groez, with a passage grave, and a curvilinear enclosure of about
Serge Cassen +2 more
doaj +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
The engraved monoliths in the Mané er Groez Neolithic passage tomb in Kercado (Carnac, Morbihan)
Gallia Préhistoire, 2018 The site of Kercado, in Carnac, is situated above the valley of Kerloquet and the ria that runs along the beach of Kerdual for 2 km. It comprises a probable low mound, the cairn of Mané er Groez, with a passage grave, and a curvilinear enclosure of about
Serge Cassen +2 more
doaj +1 more source
Sanded steps, standing over stones (2017, 2018) [REF2021 collection]
, 2021 Sanded Steps, Standing Over Stones is a live art work that rethinks ‘trace’ and ‘event’ in historical––and ongoing aporetic––situations that become self-effacing and unhappening.
Luzar, R
core
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source