Results 91 to 100 of about 12,387,393 (211)

Superantigens in Cancer Immunotherapy: Mechanisms, Engineering Strategies, and Therapeutic Potential

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
Schematic overview of superantigen‐mediated antitumor immune responses and immune suppression within the tumor microenvironment. (1) Antigen‐presenting cells activate T cells through MHC‐II/TCR interactions resulting in the production of cytokines (2) The pro‐inflammatory cytokines released by activated immune cells stimulate downstream immune ...
Urooj Yousaf Virk, Hafiza Aasia Malik, Muneera Anwer, Jennifer Wilson, Md. Sifat Rahi, Ming Q. Wei   +5 more
wiley   +1 more source

Neutrophil migration induced by staphylococcal enterotoxin type A in mice: a pharmacological analysis

, 2015
Staphylococcal enterotoxin type A induced marked neutrophil migration into the mouse peritoneal cavity and was dependent on the number of resident macrophages. This migratory response was dose- (16-64 mu g of staphylococcal enterotoxin type A/cavity) and
Desouza, IA, Ribeiro-DaSilva, G
core   +1 more source

Engineering Human Donor Derived Germinal Center‐Like Organoids (GCLOs) for Studying Immune Response to Vaccination

Advanced Science, Volume 13, Issue 53, 24 September 2026.
We bioengineered a new approach methodology of generating Germinal Center Organoids that self‐organize from human blood‐derived immune cells. These immune organoids reproduce key features of humoral immunity, IgG production, and plasmablast emergence.
Bhumi Suthar, Carlos Gomez, Giancarlo Asencio, Suresh Pallikkuth, Ashutosh Agarwal   +4 more
wiley   +1 more source

Engineering Antibodies into Targeted Chimeras: From Recognition Modules to Programmable Degraders

Advanced Science, Volume 13, Issue 50, 7 September 2026.
Antibody can be engineered into diverse lysosome‐targeting chimeras that convert target recognition into active degradation. By coupling antibody binding with recruited receptors, encoded domains, conjugated ligands, or nanoparticle scaffolds, these antibody‐associated targeted chimeras (AbTACs) platforms direct extracellular and membrane proteins ...
Kaige Chen, Quanyin Hu
wiley   +1 more source

Major Families of Multiresistant Plasmids from Geographically and Epidemiologically Diverse Staphylococci [PDF]

, 2011
Staphylococci are increasingly aggressive human pathogens suggesting that active evolution is spreading novel virulence and resistance phenotypes. Large staphylococcal plasmids commonly carry antibiotic resistances and virulence loci, but relatively few ...
Shearer, Julia E., Jensen, Slade O. (R16034), Lindsay, J., Summers, A., Mankin, A., Hostetler, J, Wireman, J, Jon Borman, Hostetler, Jessica, O'Brien, Frances G., Ronald A Skurray, Slade O Jensen, Hostetler, J., Nicholson, A., Summers, Anne O., Summers, AO, Susan Sanchez, Gill, J., Firth, Neville, Skurray, R., Gill, John, Bayles, K, Ainsley Nicholson, Lindsay, JA, Jacqueline LaMarre, Kenneth Bayles, Jodi A Lindsay, Skurray, RA, Alexander Mankin, O'Brien, Frances, Jensen, Slade O., Bayles, K., Bayles, Kenneth W., Borman, J., Jensen, SO, Gill, J, Sanchez, Susan, Forberger, H, Sanchez, S, Forberger, H., LaMarre, J., Anne O Summers, Firth, N, Shearer, J., O\u27Brien, Frances, Mankin, A, Forberger, Heather, Lindsay, Jodi A., Borman, Jon, Shearer, JE, Mankin, Alexander, Heather Forberger, Lamarre, Jacqueline, John Gill, Frances O’Brien, Jensen, S., Bayles, Kenneth, Wireman, Joy, Nicholson, A, Sanchez, S., Jessica Hostetler, Lamarre, J, Firth, N., O'Brien, F, Wireman, J., Borman, J, Julia E S Shearer, Skurray, Ronald A., Neville Firth, Nicholson, Ainsley, Joy Wireman, Shearer, Julia E.S.   +71 more
core   +1 more source

Structural insights into Clostridium perfringens delta toxin pore formation [PDF]

, 2013
Clostridium perfringens Delta toxin is one of the three hemolysin-like proteins produced by C. perfringens type C and possibly type B strains. One of the others, NetB, has been shown to be the major cause of Avian Nectrotic Enteritis, which following the
Claire E Naylor, Gibert, M., Popoff, Michel, Popoff, M.R., Motta, A., Michel R Popoff, Christos G Savva, Jessica Huyet (425370), Ajit K. Basak (425373), Michel R. Popoff, Huyet Jessica, Naylor, Claire E., Basak Ajit K., Gibert, Maryse, Basak, Ajit,, Claire E. Naylor (425371), Ajit K. Basak, Savva Christos G., Michel R. Popoff (147963), Motta, Andrea, Claire E. Naylor, Basak, Ajit, K, Huyet, Jessica, Basak, Ajit K., Savva, Christos, G, Popoff Michel R., Naylor, Claire, E, Naylor Claire E., Ajit K Basak, Christos G. Savva (425372), Gibert Maryse, Naylor, Claire,, Savva, Christos,, Christos G. Savva, Maryse Gibert, Jessica Huyet, Maryse Gibert (269234), Savva, Christos G.   +37 more
core   +1 more source

Rhinosinusitis derived Staphylococcal enterotoxin B possibly associates with pathogenesis of ulcerative colitis

BMC Gastroenterology, 2005
Background During clinical practice, we noticed that some patients with both ulcerative colitis (UC) and chronic rhinosinusitis (CRS) showed amelioration of UC after treatment of CRS. This study was designed to identify a possible association between CRS
An Zi-Yuan, Zhang Tao-Yuan, Wang Bin-Quan, Liu Tao, Yang Ping-Chang, Zheng Peng-Yuan, Tian Dao-Fa   +6 more
doaj   +1 more source

Characterisation of methicillin-susceptible Staphylococcus pseudintermedius isolates from canine infections and determination of virulence factors using multiplex PCR

Veterinární Medicína, 2017
Staphylococcus pseudintermedius is a genuine opportunistic pathogen of the skin, especially in canids. However, characterisation of virulence, antimicrobial resistance and genotypic variability in methicillin-susceptible S.
O. Melter, P. Svec, J. Tkadlec, J. Doskar, H. Kinska, R. Pantucek   +5 more
doaj   +1 more source

Therapeutic Down-Modulators of Staphylococcal Superantigen-Induced Inflammation and Toxic Shock

Toxins, 2010
Staphylococcal enterotoxin B (SEB) and related superantigenic toxins are potent stimulators of the immune system and cause a variety of diseases in humans, ranging from food poisoning to toxic shock. These toxins bind directly to major histocompatibility
Teresa Krakauer
doaj   +1 more source

Staphylococcal enterotoxin B: immunolabeling and visualization of target cells.

, 1991
Binding of staphylococcal enterotoxin B (SEB) to cultured cells and to tissue sections containing presumed target sites was detected by use of an immunofluorescence sandwich technique.
R K Nauman, M Jett, J G Olenick
core   +1 more source