Results 101 to 110 of about 115,418 (304)

Inflammatory cytokines and biofilm production sustain Staphylococcus aureus outgrowth and persistence: A pivotal interplay in the pathogenesis of Atopic Dermatitis [PDF]

, 2018
Individuals with Atopic dermatitis (AD) are highly susceptible to Staphylococcus aureus colonization. However, the mechanisms driving this process as well as the impact of S. aureus in AD pathogenesis are still incompletely understood.
A Matlow, A Oliveira de, A Sandilands, A Sonesson, AC Krakowski, AD Irvine, AM Bowcock, B Cabanillas, B Han, BC Friedman, C Fux, C Pascolini, CI Ewing, CL Jinnestal, D Ellinghaus, D Lebeaux, DY Koller, DYM Leung, DYM Leung, E Clark, E Weinberg, EC Clark, EG Domenico Di, EG Domenico Di, FJ Bath-Hextall, FR Menegotto, G Stinco, GF Gad, GL Hazelbauer, GM O’Regan, GM O’Regan, GU Meduri, H Akiyama, HB Allen, HH Kong, I Marenholz, I Nomura, J Oh, J Schmitt, JH Lee, JM Hanifin, JQ Gong, K Becker, K Breuer, K Krause, KL Hon, L Chronopoulou, L Paternoster, LA O’Neill, LP Girard, M Bhattacharya, M Denis, M Mehrotra, M Niebuhr, MD Howell, ML Schuttelaar, MS Haque, P Castaneda, P Chavant, PH Hoeger, R Lever, R Saginur, RA McLaughlin, RL Gallo, RM Klevens, RP Howlin, S Eriksson, S Kanangat, S Kezic, S Kezic, S Stutte, S Weidinger, SE Hill, SE Satorres, SE Satorres, SH Cho, SH Hung, SJ Gilani, SX Xu, T Bieber, T Biedermann, T Kobayashi, T Nakatsuji, T Werfel, TX Nhan, UG Meduri, V Dossow von, W Abramovits, Z Ikezawa   +88 more
core   +1 more source

Quantitative Mass Spectrometry‐Based Biodistribution of Monoclonal Antibodies: An Alternative to Radio‐Biodistribution

Advanced Science, EarlyView.
Monoclonal antibodies are powerful anticancer therapeutics targeting tumor‐associated antigens. Mass spectrometry enables precise and accurate quantification of mAbs in tumor plasma and healthy organs. Unlike ligand binding assay and radioactivity, mass spectrometry does not suffer from matrix effects and labelling artefacts while facilitating method ...
Domenico Ravazza, Sheila Dakhel Plaza, Samuele Cazzamalli, Andrea Ciamarone, Andrea Galbiati, Riccardo Stucchi, Frederik Peissert, Emanuele Puca, Dario Neri, Ettore Gilardoni   +9 more
wiley   +1 more source

Direct susceptibility testing by disk diffusion on clinical samples : a rapid and accurate tool for antibiotic stewardship [PDF]

, 2015
We compared the accuracy of direct susceptibility testing (DST) with conventional antimicrobial susceptibility testing (AST), both using disk diffusion, on clinical samples.
Boelens, Jerina, Claeys, Geert, Coorevits, Liselotte   +2 more
core   +3 more sources

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

Enzymatic DNA Reaction Networks for Orchestrating Stimuli‐Dependent Temporal Molecular Pulse

Advanced Science, EarlyView.
We present an enzymatic DNA reaction network (EDRN) that encodes nucleic‐acid targets in time, converting inputs into a universal strand and then into programmable transient fluorescence pulses. With time‐color multiplexing, EDRN enables single‐tube high‐plex nucleic acid detection and shows strong agreement with clinical sequencing across 32 specimens.
Jiayu Yang, Yali Chang, Zibin Chu, Linghao Zhang, Tengfang Zhang, Dai Erhei, Xin Su, Zhe Yin   +7 more
wiley   +1 more source

Risk factors for central venous catheter-related infections in surgical and intensive care units. The Central Venous Catheter-Related Infections Study Group. [PDF]

, 1994
To identify avoidable risk factors for central venous catheter (CVC) infections in patients undergoing short-term ...
Cozzi Lepri, A, Moro, ML, Viganò, EF
core   +1 more source

MEANS FOR INHIBITION OF PRODUCTION OF STAPHYLOCOCCUS ENTEROTOXINS AND THEIR ELIMINATION FROM BIOLOGICAL SUBSTRATES

Журнал микробиологии, эпидемиологии и иммунобиологии, 2017
Aim. Expansion of arsenal of means capable of inhibiting production of staphylococci entero-toxins (SE) and having an ability to eliminate them from biological substrates, as well as reducing the growth of staphylococci. Materials and methods.
F. S. Fluer, A. V. Kudryavtseva, S. I. Titarev, I. B. Bykova   +3 more
doaj   +1 more source

Stress History Establishes a Transient Tolerant State That Shapes Antibiotic Survival Upon Resuscitation

Advanced Science, EarlyView.
High‐throughput single‐cell analysis of resuscitating bacteria reveals a starvation‐history‐dependent transiently tolerant subpopulation that survives β$\beta$‐lactam exposure by temporarily reducing growth. Distinct from classical persisters, these actively growing yet dynamically modulated cells dominate survival across clinically relevant antibiotic
Kieran Abbott, Georgeos Hardo, Ruizhe Li, Jack Bradley, Ashraf Zarkan, Somenath Bakshi   +5 more
wiley   +1 more source

Inducible Clindamycin Resistance among Staphylococci Isolated from Burn Patients

Libyan Journal of Medicine, 2009
Clindamycin has been used successfully to treat pneumonia and soft-tissue infections caused by methicillin-resistant Staphylococcus aureus. However, inducible clindamycin resistance has been described as a cause of treatment failure of such infections. A
KS Ghenghesh, E El-Turki, K Tawil, O Shawerf, A Zorgani   +4 more
doaj  

A Chirality‐Converted Bacteriolytic Dodecapeptide Regulates Vibrio‐Induced Polymicrobial Infection and Ameliorates Invasion‐Associated Gut Microbiota Disequilibrium

Advanced Science, EarlyView.
Multidrug‐resistant Vibrio infections are rising rapidly and threaten coastal populations worldwide. This study introduces D‐zp37, a chirality‐engineered antimicrobial peptide with exceptional potency against resistant Vibrio species. D‐zp37 kills planktonic cells, blocks mixed‐species biofilms, disrupts essential bacterial stress responses, and shows ...
Ping Zeng, Qipeng Cheng, Xiaoxu Zhang, Honglan Wang, Jinghan Zhang, Xinyi Ding, Pengfei Zhang, Lanhua Yi, Kwok‐Yin Wong, Kin‐Fai Chan, Sheng Chen, Sharon Shui Yee Leung   +11 more
wiley   +1 more source