Results 151 to 160 of about 165,006 (216)

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

open access: yesAdvanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen   +22 more
wiley   +1 more source

RiboMicrobe: An Integrated Translatome Atlas for Microorganism

open access: yesAdvanced Science, EarlyView.
RiboMicrobe is a comprehensive database for Ribo‐seq data from prokaryotes, featuring 891 Ribo‐seq, 369 RNA‐seq, and 62 proteome datasets from 38 species. The database not only provides various data visualization results but also includes two sORF prediction models and a suit of bioinformatics tools for comparative analysis, facilitating easy access ...
Yingshun Zhou   +12 more
wiley   +1 more source

Wearable and Implantable Devices for Continuous Monitoring of Muscle Physiological Activity: A Review

open access: yesAdvanced Science, EarlyView.
Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao   +4 more
wiley   +1 more source

Editorial: Phenotypic variation as an important aspect of staphylococcal pathogenesis

open access: yesFrontiers in Cellular and Infection Microbiology
Agnieszka Bogut, Agnieszka Magryś
doaj   +1 more source

Quantification of Antibiotic Diffusion in Biofilms Using Gold Nanostar Surface‐enhanced Raman Spectroscopy

open access: yesAdvanced Science, EarlyView.
Gold nanostar‐enhanced Raman spectroscopy (SERS) enables real‐time, label‐free tracking of levofloxacin diffusion in intact biofilms. Nanostars embedded 16 µm below the surface detect drug arrival over time, revealing the impact of the biofilm matrix on antibiotic transport. Abstract The increased resistance to antibiotics shown by bacteria in biofilms
Wafaa Aljuhani   +4 more
wiley   +1 more source

Single‐Cell Insights Into Macrophage Subtypes in Pulmonary Infections

open access: yesAdvanced Science, EarlyView.
This review highlights the dynamic plasticity of macrophages during pulmonary infections and proposes an integrative framework defining six functional subtypes: Inflam‐Ms, Hub‐Ms, Reg‐Ms, Prolif‐Ms, Memory‐Ms, and Senesc‐Ms. Single‐cell omics delineate their distinct roles in homeostasis and infection, refining our understanding of macrophage ...
Zhaoheng Lin   +3 more
wiley   +1 more source

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