Results 61 to 70 of about 773,961 (344)

Staphylococcus epidermidis—Skin friend or foe?

PLoS Pathogens, 2020
Author summary Our skin is our first line of defense against environmental and pathogenic challenges. It is densely populated by a flora of bacteria, fungi, and viruses that normally interact with each other and with our immune system to promote skin ...
Morgan M Brown, A. Horswill
semanticscholar   +1 more source

Microbubble‐Controlled Delivery of Biofilm‐Targeting Nanoparticles to Treat MRSA Infection

Advanced Functional Materials, EarlyView.
Here, an effective strategy using microbubble (MB)‐controlled delivery of biofilm‐targeting nanoparticles (BTNs) for removal and therapy of methicillin‐resistant Staphylococcus aureus (MRSA) biofilm infections is introduced. In vivo delivery of MB with BTN is demonstrated to silence key bacterial genes involved in biofilm formation (icaA), bacterial ...
Ju Yeon Chung, Yujin Ahn, Joo Hun Lee, Seungju Yang, Seung Cheol Lee, Hyunjoon Kong, Hyun Jung Chung   +6 more
wiley   +1 more source

Intracellular adhesion gene expression studies in biofilm-forming of Staphylococcus aureus isolated from different clinical sources in Bagdad, Iraq [PDF]

Microbes and Infectious Diseases
Background: Staphylococcus aureus (S. aureus) a pathogenic bacterium typically found in the population is noteworthy for its pathogenicity due to its ability to produce biofilms with high virulence.
Susan Khadhem, Yaseen Motea
doaj   +1 more source

Staphylococcus aureus Toxins and Their Molecular Activity in Infectious Diseases

Toxins, 2018
Staphylococcus aureus is a microorganism resident in the skin and nasal membranes with a dreadful pathogenic potential to cause a variety of community and hospital-acquired infections.
Diana Oliveira, A. Borges, M. Simões
semanticscholar   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Therapeutic implications of C. albicans-S. aureus mixed biofilm in a murine subcutaneous catheter model of polymicrobial infection

Virulence, 2021
Biofilm-associated polymicrobial infections tend to be challenging to treat. Candida albicans and Staphylococcus aureus are leading pathogens due to their ability to form biofilms on medical devices.
Taissa Vila, Eric F. Kong, Daniel Montelongo-Jauregui, Patrick Van Dijck, Amol C. Shetty, Carrie McCracken, Vincent M. Bruno, Mary Ann Jabra-Rizk   +7 more
doaj   +1 more source

Comparison of mortality associated with methicillin-resistant and methicillin-susceptible Staphylococcus aureus bacteremia: a meta-analysis.

Clinical Infectious Diseases, 2003
A meta-analysis was performed to summarize the impact of methicillin-resistance on mortality in Staphylococcus aureus bacteremia. A search of the MEDLINE database for studies published during the period of 1 January 1980 through 31 December 2000 and a ...
S. Cosgrove, G. Sakoulas, E. Perencevich, M. Schwaber, A. Karchmer, Y. Carmeli   +5 more
semanticscholar   +1 more source

Bio‐Responsive Hydrogel for Targeted on‐Demand Release of a Phage Cocktail for Treatment of Pseudomonas aeruginosa Infection

Advanced Functional Materials, EarlyView.
This study presents an injectable hydrogel that responds to Pseudomonas aeruginosa infection by releasing a dual‐phage cocktail on demand. The system degrades selectively in infected wounds, enhances phage localization and stability, and shows potent antibiofilm activity and biocompatibility in an ex vivo human skin model—offering a promising strategy ...
Siyuan Tao, Anna Hu, Elnaz Bavel, Chien‐Hsun Yu, Sixuan Zhang, Vera Maria Kissling, Zhihao Li, Thomas Fintan Moriaty, Katharina Maniura‐Weber, Qun Ren   +9 more
wiley   +1 more source

Enhanced Sonodynamic Bacterial Elimination and Wound Healing Therapy Based on Lanthanide Ion Doped Bi2WO6 Nanosheets and Hydrogel Platform

Advanced Functional Materials, EarlyView.
Lanthanide ytterbium ions are introduced into Bi2WO6 nanosheets to boost ROS generation under US stimulation. These ytterbium‐doped Bi2WO6 nanosheets serve as efficient sonosensitizers, enabling broad‐spectrum bacterial eradication. To improve biocompatibility for in vivo sonodynamic therapy, the sonosensitizers are integrated into hydrogel matrix ...
Xinyue Lao, Qianqian Bai, Yifei Zhao, Xingyi Dai, Yuan Liu, Xiao Han, Jianhua Hao   +6 more
wiley   +1 more source

Evaluation of Wi-Fi Radiation Effects on Antibiotic Susceptibility, Metabolic Activity and Biofilm Formation by Escherichia Coli 0157H7, Staphylococcus Aureus and Staphylococcus Epidermis [PDF]

Journal of Biomedical Physics and Engineering, 2019
Background: The radiation emitted from electromagnetic fields (EMF) can cause biological effects on prokaryotic and eukaryotic cells, including non-thermal effects.
I H Said-Salman, F A Jebaii, H H Yusef, M E Moustafa   +3 more
doaj   +1 more source