Results 251 to 260 of about 4,162,760 (300)

NUB1 Regulates Muscle Atrophy in Lung Cancer Cachexia via NF‐κB Signaling Pathway

open access: yesAdvanced Science, EarlyView.
ABSTRACT Cancer‐associated cachexia (CAC) is a devastating multifactorial syndrome characterized by progressive skeletal muscle atrophy. Its mechanisms remain incompletely clarified, with limited effective therapeutic targets. NUB1, a negative regulator of ubiquitin‐like proteins mediating protein degradation, has not been fully elucidated in CAC ...
Yuqi Han   +13 more
wiley   +1 more source

Genome-scale perturb-seq in primary human CD4<sup>+</sup> T cells maps context-specific regulators of T cell programs and human immune traits. [PDF]

open access: yesCell
Zhu R   +12 more
europepmc   +1 more source

Rational Surface Engineering Reduces Advanced Glycation End‐Product Adsorption and Improves Implant Integration

open access: yesAdvanced Science, EarlyView.
Targeted surface chemical modification prevents the accumulation of advanced glycation end products (AGEs) on implant surfaces, attenuates inflammation and fibrosis, effectively restores angiogenic activity, and improves osseointegration under diabetic conditions.
Thien Ngoc Le   +13 more
wiley   +1 more source

Dual roles of AXIN1 as a β-catenin p-S60-dependent cytokinesis machinery and an ESCRT component. [PDF]

open access: yesiScience
Lee NG   +9 more
europepmc   +1 more source

3′‐UTR Hypermethylation and ABA Signaling Coordinate Transcriptional Activation of SWEET14 for High Sugar Accumulation in Citrus

open access: yesAdvanced Science, EarlyView.
Hypermethylation of CliSWEET14 3′‐UTR relieves ClibHLH105‐mediated transcriptional repression, together with ABA signaling‐mediated activation of the CliABF3‐CliNAC56 cascade, boosts CliSWEET14 expression and sucrose accumulation in citrus. ABSTRACT Sugar accumulation is pivotal for fruit quality, yet the molecular regulation of this process remains ...
Yike Zeng   +13 more
wiley   +1 more source

A Novel Sequencing Method for Quantification of ZIKV RNA in Individual Cells. [PDF]

open access: yesBio Protoc
Hao M   +13 more
europepmc   +1 more source

Molecular phylogenetics of Kashmir catfish (<i>Glyptothorax kashmirensis</i>): Genetic identity, conservation units, and basin connectivity. [PDF]

open access: yesiScience
Gilani N   +13 more
europepmc   +1 more source

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