Results 91 to 100 of about 440,600 (338)

Comparing the relation between star formation and galaxy mass in different environments [PDF]

open access: yes, 2009
Analyzing 24 mu m MIPS/Spitzer data and the [O II]3727 line of a sample of galaxies at 0.4 < z < 0.8 from the ESO Distant Cluster Survey (EDisCS), we investigate the ongoing star formation rate (SFR) and the specific star formation rate (SSFR) as a ...
Bai   +23 more
core   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A Long-Period Totally Eclipsing Binary Star at the Turnoff of the Open Cluster NGC 6819 Discovered with Kepler

open access: yes, 2012
We present the discovery of the totally eclipsing long-period (P = 771.8 d) binary system WOCS 23009 in the old open cluster NGC 6819 that contains both an evolved star near central hydrogen exhaustion and a low-mass (0.45 Msun) star.
Brewer, Lauren N.   +13 more
core   +1 more source

Star Clusters [PDF]

open access: yes, 1994
This review concentrates almost entirely on globular star clusters. It emphasises the increasing realisation that few of the traditional problems of star cluster astronomy can be studied in isolation: the influence of the Galaxy affects dynamical evolution deep in the core, and the spectrum of stellar masses; in turn the evolution of the core ...
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The 3D Kinematics of the Orion Nebula Cluster. II. Mass-dependent Kinematics of the Inner Cluster

open access: yesThe Astrophysical Journal
We present the kinematic analysis of 246 stars within $4^{\prime} $ from the center of Orion Nebula Cluster (ONC), the closest massive star cluster with active star formation across the full mass range, which provides valuable insights in the formation ...
Lingfeng Wei   +5 more
doaj   +1 more source

Radio Triggered Star Formation in Cooling Flows

open access: yes, 1999
The giant galaxies located at the centers of cluster cooling flows are frequently sites of vigorous star formation. In some instances, star formation appears to have been triggered by the galaxy's radio source.
Allen   +34 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Gamma/delta T cells as cellular vehicles for anti-tumor immunity

open access: yesFrontiers in Immunology
Adoptive cellular immunotherapy as a new paradigm to treat cancers is exemplified by the FDA approval of six chimeric antigen receptor-T cell therapies targeting hematological malignancies in recent years.
Chelsia Qiuxia Wang   +3 more
doaj   +1 more source

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