Results 71 to 80 of about 440,600 (338)
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Starburst galaxies in the Hydra I cluster
Studying the impact of environment on star formation and quenching pathways requires statistically relevant samples of galaxies in a wide mass range. We present a new catalog of 196 galaxies of the nearby Hydra I cluster out to ∼1.75r200, consisting of ...
de la Casa Clara C. +12 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
A Tale of Three Dwarfs: Cluster-based Star Formation Histories of Blue Compact Dwarf Galaxies
We present a new study of the cluster populations in the blue compact dwarf galaxies (BCD) ESO185-IG13, ESO338-IG04, and Haro11, based on new and archival high-resolution images taken by the Hubble Space Telescope, and the first to probe the populations ...
Rupali Chandar +11 more
doaj +1 more source
ACCESS III: The Nature of Star Formation in the Shapley Supercluster
We present a joint analysis of panoramic Spitzer/MIPS mid-infrared and GALEX ultraviolet imaging of the Shapley supercluster at z=0.048. Combining this with spectra of 814 supercluster members and 1.4GHz radio continuum maps, this represents the largest ...
A. Mercurio +152 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Cluster Formation in a Filamentary Cloud: The Case of the Stellar Cluster NGC 2316
We present a multiwavelength analysis of the star cluster NGC 2316 and its surroundings. We estimated the physical parameters of the NGC 2316 cluster, including its shape (elongated), size ( R _cluster = 0.4 pc), distance (1.3 ± 0.3 kpc), and minimum ...
Saurabh Sharma +9 more
doaj +1 more source
This Is Not a Myeloproliferative Neoplasm…
Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source

