Results 31 to 40 of about 91,664 (267)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

A Tale of Three Dwarfs: Cluster-based Star Formation Histories of Blue Compact Dwarf Galaxies

The Astrophysical Journal
We present a new study of the cluster populations in the blue compact dwarf galaxies (BCD) ESO185-IG13, ESO338-IG04, and Haro11, based on new and archival high-resolution images taken by the Hubble Space Telescope, and the first to probe the populations ...
Rupali Chandar, Miranda Caputo, Angus Mok, Sean Linden, Bradley C. Whitmore, Paul Goudfrooij, David O. Cook, Daniela Calzetti, Debra M. Elmegreen, Janice C. Lee, Leonardo Úbeda, Richard White   +11 more
doaj   +1 more source

Double Star/Cluster observation of neutral sheet oscillations on 5 August 2004 [PDF]

Annales Geophysicae, 2005
Previous Cluster observations have shown that the flapping motions of the Earth's magnetotail are of internal origin and that kink-like waves are emitted from the central part of the tail and propagate toward the tail flanks. The newly launched Double
T. L. Zhang, T. L. Zhang, R. Nakamura, M. Volwerk, M. Volwerk, A. Runov, W. Baumjohann, H. U. Eichelberger, C. Carr, A. Balogh, V. Sergeev, J. K. Shi, K.-H. Fornacon   +12 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Cluster Formation in a Filamentary Cloud: The Case of the Stellar Cluster NGC 2316

The Astronomical Journal
We present a multiwavelength analysis of the star cluster NGC 2316 and its surroundings. We estimated the physical parameters of the NGC 2316 cluster, including its shape (elongated), size ( R _cluster = 0.4 pc), distance (1.3 ± 0.3 kpc), and minimum ...
Saurabh Sharma, Aayushi Verma, Kshitiz Mallick, Lokesh K. Dewangan, Harmeen Kaur, Ram Kesh Yadav, Neelam Panwar, Devendra K. Ojha, Tarak Chand, Mamta Agarwal   +9 more
doaj   +1 more source

Outflows Driven by Direct and Reprocessed Radiation Pressure in Massive Star Clusters [PDF]

, 2022
Shyam H. Menon, Christoph Federrath, Mark R. Krumholz   +2 more
openalex   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source