Results 41 to 50 of about 91,664 (267)
Dynamics of Star Cluster Formation: The Effects of Ongoing Star Formation and Stellar Feedback
We perform a high-resolution zoomed-in simulation of star cluster assembly including the merger of two subclusters with initial conditions taken from previous large-scale giant molecular cloud (GMC) simulations.
Jeremy Karam +2 more
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
We analyze deep ( M _* ≳ 10 ^7 M _⊙ ) galaxy stellar mass functions (SMFs) of the Virgo cluster using stellar masses derived as part of the Next Generation Virgo Survey. The total SMF has a slope of $\alpha =-1.3{5}_{-0.02}^{+0.02}$ , which is similar to
Cameron R. Morgan +10 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Star-forming galaxies in galaxy clusters play a crucial role in understanding the advanced stages of galaxy evolution within dense environments. We present a sample of 3.3 μ m polycyclic aromatic hydrocarbon (PAH)-bright galaxies in the A2744 galaxy ...
Cheng Cheng +9 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The 3D Kinematics of the Orion Nebula Cluster. II. Mass-dependent Kinematics of the Inner Cluster
We present the kinematic analysis of 246 stars within $4^{\prime} $ from the center of Orion Nebula Cluster (ONC), the closest massive star cluster with active star formation across the full mass range, which provides valuable insights in the formation ...
Lingfeng Wei +5 more
doaj +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Gamma/delta T cells as cellular vehicles for anti-tumor immunity
Adoptive cellular immunotherapy as a new paradigm to treat cancers is exemplified by the FDA approval of six chimeric antigen receptor-T cell therapies targeting hematological malignancies in recent years.
Chelsia Qiuxia Wang +3 more
doaj +1 more source

