Results 121 to 130 of about 2,681,556 (391)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Semiempirical versus Theoretical Stellar Population Models: A Comparison with Star Clusters

The Astronomical Journal
Stellar population synthesis (SPS) models are a key tool for deriving the age, metallicity, radial velocity, and reddening of star clusters from their integrated spectra.
Randa Asa’d, Paula R. T. Coelho, Johina M. John, Igor V. Chilingarian, Gustavo Bruzual, Stephane Charlot   +5 more
doaj   +1 more source

Deriving physical parameters of unresolved star clusters III. Application to M31 PHAT clusters

, 2015
This study is the third of a series that investigates the degeneracy and stochasticity problems present in the determination of physical parameters such as age, mass, extinction, and metallicity of partially resolved or unresolved star cluster ...
de Meulenaer, Philippe, Mineikis, Tadas, Narbutis, Donatas, Vansevičius, Vladas   +3 more
core   +2 more sources

Time resolved photoelectron spectroscopy of iodide-4-thiouracil cluster: the pi/pi star state as a doorway for electron attachment [PDF]

, 2023
Megan Asplund, Masafumi Koga, Ying Jung Wu, Daniel M. Neumark   +3 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Massive Star Cluster Formation with Binaries. I. Evolution of Binary Populations

The Astrophysical Journal
We study the evolution of populations of binary stars within massive cluster-forming regions. We simulate the formation of young massive star clusters within giant molecular clouds with masses ranging from 2 × 10 ^4 to 3.2 × 10 ^5 M _⊙ .
Claude Cournoyer-Cloutier, Alison Sills, William E. Harris, Brooke Polak, Steven Rieder, Eric P. Andersson, Sabrina M. Appel, Mordecai-Mark Mac Low, Stephen McMillan, Simon Portegies Zwart   +9 more
doaj   +1 more source

Extreme Star Formation

, 2009
Extreme star formation includes star formation in starbursts and regions forming super star clusters. We survey the current problems in our understanding of the star formation process in starbursts and super star clusters - initial mass functions ...
Turner, Jean L.
core   +2 more sources

The Hierarchical Distribution of the Young Stellar Clusters in Six Local Star-forming Galaxies [PDF]

, 2017
We present a study of the hierarchical clustering of the young stellar clusters in six local (3–15 Mpc) star-forming galaxies using Hubble Space Telescope broadband WFC3/UVIS UV and optical images from the Treasury Program LEGUS (Legacy ExtraGalactic UV ...
K. Grasha, D. Calzetti, A. Adamo, Hwihyun Kim, B. Elmegreen, D. Gouliermis, D. Gouliermis, D. Dale, M. Fumagalli, E. Grebel, Kelsey E. Johnson, L. Kahre, R. Kennicutt, M. Messa, A. Pellerin, J. Ryon, Linda J. Smith, F. Shabani, D. Thilker, L. Úbeda   +19 more
semanticscholar   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

The temporal and spatial evolution of the starburst in ESO 338-IG04 as probed by its star clusters

, 2003
In this paper we use ultra-violet (UV) and optical HST photometry in five bands, and an extensive set of spectral evolutionary synthesis scenarios to investigate the age and masses of 124 star clusters in the luminous blue compact galaxy ESO338-IG04 ...
Bergvall, Bergvall, Bergvall, Brodie, Buat, Calzetti, Calzetti, Charlot, De Grijs, Dulzin-Hacyan, E. Zackrisson, Fall, Förster Schreiber, G. Östlin, Genzel, Guzmán, Hopkins, J. Rönnback, Kassim, Kroupa, Kunth, Le Fèvre, Lejeune, Lilly, Madau, Mas-Hesse, Massey, Maíz-Appelániz, McKee, McLaughlin, Meurer, Meylan, Middlemass, Miller, N. Bergvall, Pandey, Pascarelle, Peimbert, Raimann, Salpeter, Schulte-Ladbeck, Searle, Seaton, Serabyn, Tashiro, Vacca, Whitmore, Whitmore, Williams, Williams, Zackrisson, Zepf, Zhang, Östlin, Östlin, Östlin   +55 more
core   +1 more source