Results 201 to 210 of about 2,681,556 (391)

Interplay between RNA‐protein interactions and RNA structures in gene regulation

open access: yesFEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko   +2 more
wiley   +1 more source

Discovery of 178 Open Clusters with Gaia DR3

open access: yesThe Astronomical Journal
We present 178 new open cluster candidates identified through the application of the HDBSCAN clustering algorithm to astrometric data from the Gaia DR3 catalog.
Wilton S Dias   +4 more
doaj   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

open access: yesFEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul   +3 more
wiley   +1 more source

JWST Observations of Starbursts: Massive Star Clusters in the Central Starburst of M82

open access: yesThe Astrophysical Journal Letters
We present a near-infrared (NIR) candidate star cluster catalog for the central kiloparsec of M82 based on new JWST NIRCam images. We identify star cluster candidates using the F250M filter, finding 1357 star cluster candidates with stellar masses >10 ^4
Rebecca C. Levy   +27 more
doaj   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Seeding Cores: A Pathway for Nuclear Star Clusters from Bound Star Clusters in the First Billion Years

open access: yesThe Open Journal of Astrophysics
We model the formation of star clusters in a dwarf galaxy progenitor during the first 700 Myr of cosmic history using a cosmological radiation-hydrodynamic simulation with a sub-grid star formation efficiency (SFE) model calibrated from AU-scale ...
Fred Angelo Batan Garcia   +2 more
doaj   +1 more source

The life cycle of star clusters in a tidal field [PDF]

open access: green, 2011
Mark Gieles   +2 more
openalex   +1 more source

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