Results 101 to 110 of about 976,493 (346)
FEBS Letters, EarlyView.Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria +3 more
wiley +1 more source
Revealing Multiple Nested Molecular Outflows with Rotating Signatures in HH270mms1-A with ALMA
The Astrophysical JournalWe present molecular line observations of the protostellar outflow associated with HH270mms1 in the Orion B molecular cloud with ALMA. The ^12 CO ( J = 3−2) emissions show that the outflow velocity structure consists of four distinct components of low ...
Mitsuki Omura +2 more
doaj +1 more source
Mildly Suppressed Star Formation in Central Regions of MaNGA Seyfert Galaxies
, 2018 Negative feedback from accretion onto super-massive black holes (SMBHs), that is to remove gas and suppress star formation in galaxies, has been widely suggested.
Bing, Longji +10 more
core +1 more source
Star Formation Thresholds [PDF]
Proceedings of the International Astronomical Union, 2007 AbstractTo make predictions for the existence of “dark galaxies”, it is necessary to understand what determines whether a gas cloud will form stars. Star formation thresholds are generally explained in terms of the Toomre criterion for gravitational instability. I contrast this theory with the thermo-gravitational instability hypothesis of Schaye (2004)
openaire +3 more sources
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
The onset of star formation in primordial haloes
, 2009 Star formation remains an unsolved problem in astrophysics. Numerical studies of large-scale structure simulations cannot resolve the whole process and their approach usually assumes that only gas denser than a typical threshold can host and form stars ...
Abel +59 more
core +1 more source
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
FEBS Letters, EarlyView.MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson +7 more
wiley +1 more source
The imprint of star formation on stellar pulsations. [PDF]
Nat Commun, 2022 Steindl T, Zwintz K, Vorobyov E.
europepmc +1 more source
The turbulent formation of stars [PDF]
Physics Today, 2018 How stars are born from clouds of gas is a rich physics problem whose solution will inform our understanding of not just stars but also planets, galaxies, and the universe itself.
openaire +3 more sources
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source