Results 131 to 140 of about 5,183,495 (311)

Morphology of star formation regions in irregular galaxies [PDF]

, 1998
N. Brosch, Ana Heller, E. Almoznino
openalex   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Early-type Galaxies on the Star Formation Main Sequence: Internal Star Formation Geometries Revealed with MaNGA and Their Environmental Origin

The Astrophysical Journal
Star-forming galaxies on the main sequence (MS) are often regarded as a uniform population characterized by similar global star formation properties. However, there exists a diversity in galaxy morphologies at a fixed stellar mass and star formation rate.
Shuhei Koyama, Yusei Koyama, Takuji Yamashita, Masahiro Konishi, Kosuke Kushibiki, Kentaro Motohara   +5 more
doaj   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Efficient semi-analytic modelling of Pop III star formation from Cosmic Dawn to Reionization

The Open Journal of Astrophysics
The quest to find the first stars has driven astronomers across cosmic time, from hopes to identify their signatures in their heyday at cosmic dawn to deep searches for their remnants in our local neighborhood.
Sahil Hegde, Steven R. Furlanetto
doaj   +1 more source

High-redshift star formation in the Atacama large millimetre/submillimetre array era. [PDF]

R Soc Open Sci, 2020
Hodge JA, da Cunha E.
europepmc   +1 more source

THE ROLE OF STAR FORMATION AND AN AGN IN DUST HEATING OFz= 0.3–2.8 GALAXIES. I. EVOLUTION WITH REDSHIFT AND LUMINOSITY [PDF]

, 2015
Allison Kirkpatrick, Alexandra Pope, Anna Sajina, Eric Roebuck, Lin Yan, Lee Armus, Tanio Díaz-Santos, Sabrina Stierwalt, Allison Kirkpatrick, Alexandra Pope, Anna Sajina, Eric Roebuck, Lin Yan, Lee Armus, Tanio Díaz-Santos, Sabrina Stierwalt   +15 more
openalex   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Signatures of Mass Segregation from Competitive Accretion and Monolithic Collapse

The Astrophysical Journal
The two main competing theories proposed to explain the formation of massive (>10 M _⊙ ) stars—competitive accretion and monolithic core collapse—make different observable predictions for the environment of the massive stars during, and immediately after,
Richard J. Parker, Emily J. Pinson, Hayley L. Alcock, James E. Dale   +3 more
doaj   +1 more source