Results 151 to 160 of about 4,646,373 (300)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

PHANGS-HST Catalogs for ∼100,000 Star Clusters and Compact Associations in 38 Galaxies. I. Observed Properties

The Astrophysical Journal Supplement Series
We present the largest catalog to date of star clusters and compact associations in nearby galaxies. We have performed a V -band-selected census of clusters across the 38 spiral galaxies of the PHANGS–Hubble Space Telescope (HST) Treasury Survey, and ...
Daniel Maschmann, Janice C. Lee, David A. Thilker, Bradley C. Whitmore, Sinan Deger, Médéric Boquien, Rupali Chandar, Daniel A. Dale, Aida Wofford, Stephen Hannon, Kirsten L. Larson, Adam K. Leroy, Eva Schinnerer, Erik Rosolowsky, Leonardo Úbeda, Ashley T. Barnes, Eric Emsellem, Kathryn Grasha, Brent Groves, Rémy Indebetouw, Hwihyun Kim, Ralf S. Klessen, Kathryn Kreckel, Rebecca C. Levy, Francesca Pinna, M. Jimena Rodríguez, Qiushi Tian, Thomas G. Williams   +27 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

The ALMA-QUARKS Survey: Hot Molecular Cores Are a Long-standing Phenomenon in the Evolution of Massive Protostars

The Astrophysical Journal
We present an analysis of the QUARKS survey sample, focusing on protoclusters where hot molecular cores (HMCs; traced by CH _3 CN (12–11)) and HC/UC H ii regions (traced by H30 α /H40 α ) coexist.
Dezhao Meng, Tie Liu, Jarken Esimbek, Sheng-Li Qin, Guido Garay, Paul F. Goldsmith, Jianjun Zhou, Xindi Tang, Wenyu Jiao, Yan-Kun Zhang, Fengwei Xu, Siju Zhang, Anandmayee Tej, Leonardo Bronfman, Aiyuan Yang, Sami Dib, Swagat R. Das, Jihye Hwang, Archana Soam, Yisheng Qiu, Dalei Li, Yuxin He, Gang Wu, Lokesh Dewangan, James O. Chibueze, Pablo García, Prasanta Gorai, Naval Kishor Bhadari, Yong Zhang, Patricio Sanhueza, Yongquan Luo, Jia-Hang Zou, Kee-Tae Kim, Dongting Yang, Lei Zhu, Xunchuan Liu, Macleod Gordon, Yingxiu Ma   +37 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Cosmological galaxy formation simulations with dust

, 2016
Recent observations of galaxies in the redshift range 6.5 < z < 7.5 show an increasing evidence of a significant amount of dust ([1],[2],[3]). Intepreting the role of different stellar populations, their formation rates and the various phases of ...
LUCA GRAZIANI, Mattia Mancini, Raffaella Schneider   +2 more
core  

Star formation in the Magellanic clouds [PDF]

, 1987
Because of their proximity, the Magellanic Clouds provide the opportunity to conduct a detailed study of the history and current state of star formation in dwarf irregular galaxies. There is considerable evidence that star formation in the Clouds was and
Frogel, Jay A.
core  

The ALMA-ATOMS Survey: Methanol Emission in a Large Sample of Hot Molecular Cores

The Astrophysical Journal
Methanol (CH _3 OH) is a key complex organic molecule (COM) in the interstellar medium, widely used as a tracer of dense gas and hot molecular cores (HMCs).
Jiahang Zou, Tie Liu, Sheng-Li Qin, Yaping Peng, Fengwei Xu, Xunchuan Liu, Li Chen, Xindi Tang, Sami Dib, Zi-Yang Li, Hong-Li Liu, Mika Juvela, Patricio Sanhueza, Pablo Garcia, Chang Won Lee, Guido Garay, Swagat R. Das, Yan-Kun Zhang, Kee-Tae Kim, Jeong-Eun Lee, Meizhu Liu, Leonardo Bronfman, Zhiping Kou, Dongting Yang, Gang Wu, Jihye Hwang, Dezhao Meng, Mengyao Tang, James O. Chibueze   +28 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Measuring star formation rates in blue galaxies [PDF]

, 1987
The problems associated with measurements of star formation rates in galaxies are briefly reviewed, and specific models are presented for determinations of current star formation rates from H alpha and Far Infrared (FIR) luminosities.
Hunter, Deidre A., Gallagher, John S., III   +1 more
core