Results 171 to 180 of about 5,548,804 (305)

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

LZ-STAR Survey: Low-metallicity Star Formation Survey of Sh2-284. I. Ordered Massive Star Formation in the Outer Galaxy

Star formation is a fundamental, yet poorly understood, process of the Universe. It is important to study how star formation occurs in different galactic environments.
Kei E. I. Tanaka, Cheng, Yu, Yu Cheng, Rubén Fedriani, Massimo Robberto, Zhi-Yun Li, Andersen, Morten, Yichen Zhang, Tan, J. C., Morten Andersen, Fedriani, R., Tanaka, Kei E. I., Robberto, Massimo, Zhang, Yichen, Li, Zhi-Yun, Jonathan C. Tan, Fedriani, Rubén,, Cheng, Yu,, Robberto, Massimo,, Andersen, Morten,, Tan, Jonathan,, Tanaka, Kei E.I.,, Zhang, Yichen,, Li, Z. Y.,   +23 more
core   +1 more source

A Census of Star Formation in the Outer Galaxy: The SMOG Field. [PDF]

Astrophys J, 2019
Winston E, Hora J, Gutermuth R, Tolls V.
europepmc   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Galactic outflows and star-formation quenching: a JWST perspective. [PDF]

Astrophys Space Sci
Davies RL, Belli S.
europepmc   +1 more source

Fast and inefficient star formation due to short-lived molecular clouds and rapid feedback. [PDF]

Nature, 2019
Kruijssen JMD, Schruba A, Chevance M, Longmore SN, Hygate APS, Haydon DT, McLeod AF, Dalcanton JJ, Tacconi LJ, van Dishoeck EF.   +9 more
europepmc   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Identifying the principal mechanism of star formation feedback. [PDF]

Sci Adv
Li C, Li R, Qiu K, Krco M, Li D, Wang H, Lyu X, Duan Y, Fang M, Chen X, Wang L, Feng H, Zhang S, Zhang M, Zhang S, Cao Y, Wang Y, Gong Y, Du F, Chen Z, Su Y, Ma Y, Xing Y, Zheng Y, Zhang T, Niu S, Li C, Liu J, Zhang Z, Guo Y.   +29 more
europepmc   +1 more source