The potential of tracing the star formation history with H I 21-cm in intervening absorption systems [PDF]
, 2017 S. J. Curran
openalex +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
STAR FORMATION AT <i>Z</i> = 2.481 IN THE LENSED GALAXY SDSS J1110+6459: STAR FORMATION DOWN TO 30 PARSEC SCALES. [PDF]
Astrophys J Lett, 2017 Johnson TL +9 more
europepmc +1 more source
FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
GALAXY STRUCTURE, STELLAR POPULATIONS, AND STAR FORMATION QUENCHING AT 0.6 ≲ <i>z</i> ≲ 1.2. [PDF]
Astrophys J, 2018 Kim K +5 more
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Triggered Star Formation inside the Shell of a Wolf-Rayet Bubble as the Origin of the Solar System. [PDF]
Proc Int Astron Union, 2018 Dwarkadas VV +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Evidence for Dark Energy Driven by Star Formation: Information Dark Energy? [PDF]
Entropy (Basel)Gough MP.
europepmc +1 more source
Triggered Star Formation inside the Shell of a Wolf-Rayet Bubble as the Origin of the Solar System. [PDF]
Astrophys J, 2017 Dwarkadas VV +4 more
europepmc +1 more source