Results 131 to 140 of about 1,022,915 (352)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Revealing Multiple Nested Molecular Outflows with Rotating Signatures in HH270mms1-A with ALMA

open access: yesThe Astrophysical Journal
We present molecular line observations of the protostellar outflow associated with HH270mms1 in the Orion B molecular cloud with ALMA. The ^12 CO ( J = 3−2) emissions show that the outflow velocity structure consists of four distinct components of low ...
Mitsuki Omura   +2 more
doaj   +1 more source

The Reliability of [C II] as a Star Formation Rate Indicator

open access: yesOpen Astronomy, 2011
We present a calibration of the star formation rate (SFR) as a function of the [C II] 157.74 μm luminosity for a sample of 24 star-forming galaxies in the nearby universe.
De Looze Ilse   +4 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Local Star formation triggered by SN shocks in magnetized diffuse neutral clouds

open access: yes, 2008
In this work, considering the impact of a SNR with a neutral magnetized cloud we derived analytically a set of conditions which are favorable for driving gravitational instability in the cloud and thus star formation.
Anderson   +79 more
core   +1 more source

The spatially resolved star formation history of the dwarf spiral galaxy NGC 5474 [PDF]

open access: green, 2023
Giacomo Bortolini   +18 more
openalex   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Home - About - Disclaimer - Privacy