Results 141 to 150 of about 1,116,232 (311)

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

Radio Observations Related to Star Formation [PDF]

open access: bronze, 1977
P. G. Mezger, Lindsey F. Smith
openalex   +1 more source

Alignment Parameters: Quantifying Dense Core Alignment in Star-forming Regions

open access: yesThe Astrophysical Journal
Recent high-resolution observations at millimeter (mm) and submillimeter wavelengths reveal a diverse spatial distribution for subparsec-scale dense cores within star-forming regions, ranging from clustered to aligned arrangements.
Wei-An Chen   +3 more
doaj   +1 more source

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

A Tale of Three Dwarfs: Cluster-based Star Formation Histories of Blue Compact Dwarf Galaxies

open access: yesThe Astrophysical Journal
We present a new study of the cluster populations in the blue compact dwarf galaxies (BCD) ESO185-IG13, ESO338-IG04, and Haro11, based on new and archival high-resolution images taken by the Hubble Space Telescope, and the first to probe the populations ...
Rupali Chandar   +11 more
doaj   +1 more source

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

open access: yesMolecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang   +10 more
wiley   +1 more source

The Effects of Bar Strength and Kinematics on Galaxy Evolution: Slow Strong Bars Affect Their Hosts the Most

open access: yesThe Astrophysical Journal
We study how bar strength and bar kinematics affect star formation in different regions of the bar by creating radial profiles of EW[H α ] and D _n 4000 using data from Sloan Digital Sky Survey-IV Mapping Nearby Galaxies at Apache Point Observatory ...
Tobias Géron   +7 more
doaj   +1 more source

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