Results 141 to 150 of about 976,493 (346)

Radio Observations Related to Star Formation [PDF]

open access: bronze, 1977
P. G. Mezger, Lindsey F. Smith
openalex   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Efficient semi-analytic modelling of Pop III star formation from Cosmic Dawn to Reionization

open access: yesThe Open Journal of Astrophysics
The quest to find the first stars has driven astronomers across cosmic time, from hopes to identify their signatures in their heyday at cosmic dawn to deep searches for their remnants in our local neighborhood.
Sahil Hegde, Steven R. Furlanetto
doaj   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

Signatures of Mass Segregation from Competitive Accretion and Monolithic Collapse

open access: yesThe Astrophysical Journal
The two main competing theories proposed to explain the formation of massive (>10 M _⊙ ) stars—competitive accretion and monolithic core collapse—make different observable predictions for the environment of the massive stars during, and immediately after,
Richard J. Parker   +3 more
doaj   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

A Tale of Three Dwarfs: Cluster-based Star Formation Histories of Blue Compact Dwarf Galaxies

open access: yesThe Astrophysical Journal
We present a new study of the cluster populations in the blue compact dwarf galaxies (BCD) ESO185-IG13, ESO338-IG04, and Haro11, based on new and archival high-resolution images taken by the Hubble Space Telescope, and the first to probe the populations ...
Rupali Chandar   +11 more
doaj   +1 more source

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