Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song+13 more
wiley +1 more source
Optical distortion of M86; star formation from cooling gas? [PDF]
P. E. J. Nulsen, D. Carter
openalex +1 more source
Triggered Star Formation inside the Shell of a Wolf-Rayet Bubble as the Origin of the Solar System. [PDF]
Dwarkadas VV+4 more
europepmc +1 more source
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi+26 more
wiley +1 more source
Star Formation, Giant Hii Regions and Spiral Structure [PDF]
M. R. Rosa
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Star formation shut down by multiphase gas outflow in a galaxy at a redshift of 2.45. [PDF]
Belli S+17 more
europepmc +1 more source
Astrochemical evolution along star formation: Overview of the IRAM Large Program ASAI. [PDF]
Lefloch B+29 more
europepmc +1 more source
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam+9 more
wiley +1 more source
Centers of Star Formation in the Nuclei of Galaxies [PDF]
V. I. Pronik
openalex +1 more source
The Little Engines That Could? Globular clusters contribute significantly to reionization-era star formation. [PDF]
Boylan-Kolchin M.
europepmc +1 more source