Results 141 to 150 of about 3,871,291 (295)

Submillimetre polarimetric observations of magnetic fields in star-forming regions

, 2007
Submillimetre imaging polarimetry is one of the most powerful tools at present for studying magnetic fields in star-forming regions, and the only way to gain significant information on the structure of these fields.
Chrysostomou, Antonio, Curran, Rachel L., Matthews, Brenda C.   +2 more
core   +1 more source

Investigating the Influence of Radiative Feedback in the Bright-rimmed Cloud 44

The Astrophysical Journal
Radiative feedback from massive stars plays a central role in the evolution of molecular clouds and the interstellar medium. This paper presents a multiwavelength analysis of the bright-rimmed cloud (BRC) 44, which is located at the periphery of the H ii
Rishi C, Neelam Panwar, Thomas J. Haworth, Yan Sun, Saurabh Sharma, R. K. Yadav, D.K. Ojha, H.P. Singh, Jessy Jose, Ajay Kumar Singh, Jincen Jose, Shubham Yadav   +11 more
doaj   +1 more source

Young Stellar Objects in the Massive Star-forming Regions W51 and W43. [PDF]

Astrophys J, 2017
Saral G, Hora JL, Audard M, Koenig XP, Martínez-Galarza JR, Motte F, Nguyen-Luong Q, Saygac AT, Smith HA.   +8 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Structure of photodissociation fronts in star-forming regions revealed by observations of high-J CO emission lines with Herschel. [PDF]

Astron Astrophys, 2018
Joblin C, Bron E, Pinto C, Pilleri P, Le Petit F, Gerin M, Le Bourlot J, Fuente A, Berne O, Goicoechea JR, Habart E, Köhler M, Teyssier D, Nagy Z, Montillaud J, Vastel C, Cernicharo J, Röllig M, Ossenkopf-Okada V, Bergin EA.   +19 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

FEAST: JWST Uncovers the Emerging Timescales of Young Star Clusters in M83

The Astrophysical Journal
We present JWST NIRCam observations of the emerging young star clusters (eYSCs) detected in the nearby spiral galaxy M83. The NIRcam mosaic encompasses the nuclear starburst, the bar, and the inner spiral arms.
Alice Knutas, Angela Adamo, Alex Pedrini, Sean T. Linden, Varun Bajaj, Jenna E. Ryon, Benjamin Gregg, Ahmad A. Ali, Eric P. Andersson, Arjan Bik, Giacomo Bortolini, Anne S. M. Buckner, Daniela Calzetti, Ana Duarte-Cabral, Bruce G. Elmegreen, Helena Faustino Vieira, John S. Gallagher, Kathryn Grasha, Kelsey Johnson, Thomas S.-Y. Lai, Drew Lapeer, Matteo Messa, Göran Östlin, Elena Sabbi, Linda J. Smith, Monica Tosi   +25 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

VLA 22 GHz Imaging of Massive Star Formation in Local Wolf–Rayet Galaxies

The Astrophysical Journal
We present 22 GHz imaging of regions of massive star formation within the Local Wolf–Rayet Galaxy Sample, a NSF Karl G. Jansky Very Large Array survey of 30 local galaxies showing spectral features of Wolf–Rayet (WR) stars.
Nicholas G. Ferraro, Jean L. Turner, Sara C. Beck, Edwin Alexani, Runa Indrei, Bethany M. Welch, Tunhui Xie   +6 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source