Results 121 to 130 of about 288,104 (243)

Low-mass Stellar and Substellar Content of the Young Cluster Berkeley 59

The Astronomical Journal
We present a multiwavelength analysis of the young star cluster Berkeley 59, based on Gaia data and deep IR observations with the 3.58 m Telescopio Nazionale Galileo and Spitzer space telescope.
Neelam Panwar, Rishi C., Saurabh Sharma, Devendra K. Ojha, Manash R. Samal, H. P. Singh, Ram Kesh Yadav   +6 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Star Forming Regions in Cepheus

, 2008
104 pages, 25 tables, 35 figures; A chapter in the "Handbook of Star Forming Regions, Vol 1: The Northern Sky," ed. Bo Reipurth; ASP Monograph Series. Full resolution version can be found at http://www.konkoly.hu/staff/kun/handbook_chapters/
Kun, M., Kiss, Z. T., Balog, Z.
openaire   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

FEAST: JWST Uncovers the Emerging Timescales of Young Star Clusters in M83

The Astrophysical Journal
We present JWST NIRCam observations of the emerging young star clusters (eYSCs) detected in the nearby spiral galaxy M83. The NIRcam mosaic encompasses the nuclear starburst, the bar, and the inner spiral arms.
Alice Knutas, Angela Adamo, Alex Pedrini, Sean T. Linden, Varun Bajaj, Jenna E. Ryon, Benjamin Gregg, Ahmad A. Ali, Eric P. Andersson, Arjan Bik, Giacomo Bortolini, Anne S. M. Buckner, Daniela Calzetti, Ana Duarte-Cabral, Bruce G. Elmegreen, Helena Faustino Vieira, John S. Gallagher, Kathryn Grasha, Kelsey Johnson, Thomas S.-Y. Lai, Drew Lapeer, Matteo Messa, Göran Östlin, Elena Sabbi, Linda J. Smith, Monica Tosi   +25 more
doaj   +1 more source

Star Forming Regions in Cassiopeia

, 2008
This chapter describes the Galactic star forming regions in the constellation Cassiopeia, in the Galactic coordinate range 120 deg < l < 130 deg, -5 deg < b < +15 deg. At b > 10 deg the nearby clouds L1333 and L1340 are found in this region.
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

VLA 22 GHz Imaging of Massive Star Formation in Local Wolf–Rayet Galaxies

The Astrophysical Journal
We present 22 GHz imaging of regions of massive star formation within the Local Wolf–Rayet Galaxy Sample, a NSF Karl G. Jansky Very Large Array survey of 30 local galaxies showing spectral features of Wolf–Rayet (WR) stars.
Nicholas G. Ferraro, Jean L. Turner, Sara C. Beck, Edwin Alexani, Runa Indrei, Bethany M. Welch, Tunhui Xie   +6 more
doaj   +1 more source

Chemical evolution in high-mass star-forming regions

Frontiers in Astronomy and Space Sciences
Growing evidence shows that most stars in the Milky Way, including our Sun, are born in high-mass star-forming regions, but due to both observational and theoretical challenges, our understanding of their chemical evolution is much less clear than that ...
Francesco Fontani, Francesco Fontani, Francesco Fontani, Maria Teresa Beltrán, Anton Vasyunin   +4 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source