Results 111 to 120 of about 56,054 (306)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Lifetimes of Phases in High-mass Star-forming Regions

open access: yes, 2017
High-mass stars form within star clusters from dense, molecular regions (DMRs), but is the process of cluster formation slow and hydrostatic or quick and dynamic?
Svoboda, Brian   +2 more
core   +1 more source

The Impact of External Radiation on the Inner Disk Chemistry of Planet Formation

open access: yesThe Astrophysical Journal
The vast majority of young stars hosting planet-forming disks exist within clustered environments, like the Orion Nebula, implying that seemingly “extreme” UV environments (10 ^4 G _0 and above) are not so atypical in the context of planet formation ...
Jenny K. Calahan   +2 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Giant star-forming regions in interacting galaxies [PDF]

open access: yes
The most violent processes of star formation can be found in interacting galaxies, where gas compression can trigger the formation of giant star-forming regions. Using high-resolution spectroscopic information from MIKE/Magellan and multi- slit data from
Bosch, Guillermo Luis   +4 more
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Circumnuclear Star-forming Regions in barred Galaxies

open access: yes, 1999
We present high-resolution Hα velocity fields and rotation curves of the circum nuclear star-forming regions of five barred galaxies. Two of the five objects show substantially smaller initial rises than the three others; these two objects also have ...
Knapen, J., Laine, S., Relano, M.
core  

The JCMT Gould Belt Survey : low-mass protoplanetary discs from a SCUBA-2 census of NGC 1333

open access: yes, 2015
Date of Acceptance: 12/11/2014NGC 1333 is a 1–2 Myr old cluster of stars in the Perseus molecular cloud. We used 850 μm data from the Gould Belt Survey with SCUBA-2 on the James Clerk Maxwell Telescope to measure or place limits on disc masses for 82 ...
Hatchell, J.   +15 more
core   +1 more source

Molecular gas and star formation in GASP jellyfish galaxies

open access: yesAstronomy & Astrophysics
Context. Several studies have reported a nearly linear correlation between the molecular gas and star formation rate surface density, the so-called Kennicutt-Schmidt (KS) law. Aims.
Moretti A.   +15 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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