Results 131 to 140 of about 56,054 (306)

Star Forming Regions in Cepheus

, 2008
104 pages, 25 tables, 35 figures; A chapter in the "Handbook of Star Forming Regions, Vol 1: The Northern Sky," ed. Bo Reipurth; ASP Monograph Series. Full resolution version can be found at http://www.konkoly.hu/staff/kun/handbook_chapters/
Kun, M., Kiss, Z. T., Balog, Z.
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Mid-Infrared Imaging of Star Forming Regions

, 1996
Star formation is one of the most widely studied subjects in astronomy today, but many· aspects of the star forming process are still not well understood.
Dahm, Mary
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

FEAST: JWST Uncovers the Emerging Timescales of Young Star Clusters in M83

The Astrophysical Journal
We present JWST NIRCam observations of the emerging young star clusters (eYSCs) detected in the nearby spiral galaxy M83. The NIRcam mosaic encompasses the nuclear starburst, the bar, and the inner spiral arms.
Alice Knutas, Angela Adamo, Alex Pedrini, Sean T. Linden, Varun Bajaj, Jenna E. Ryon, Benjamin Gregg, Ahmad A. Ali, Eric P. Andersson, Arjan Bik, Giacomo Bortolini, Anne S. M. Buckner, Daniela Calzetti, Ana Duarte-Cabral, Bruce G. Elmegreen, Helena Faustino Vieira, John S. Gallagher, Kathryn Grasha, Kelsey Johnson, Thomas S.-Y. Lai, Drew Lapeer, Matteo Messa, Göran Östlin, Elena Sabbi, Linda J. Smith, Monica Tosi   +25 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

VLA 22 GHz Imaging of Massive Star Formation in Local Wolf–Rayet Galaxies

The Astrophysical Journal
We present 22 GHz imaging of regions of massive star formation within the Local Wolf–Rayet Galaxy Sample, a NSF Karl G. Jansky Very Large Array survey of 30 local galaxies showing spectral features of Wolf–Rayet (WR) stars.
Nicholas G. Ferraro, Jean L. Turner, Sara C. Beck, Edwin Alexani, Runa Indrei, Bethany M. Welch, Tunhui Xie   +6 more
doaj   +1 more source

Chemical evolution in high-mass star-forming regions

Frontiers in Astronomy and Space Sciences
Growing evidence shows that most stars in the Milky Way, including our Sun, are born in high-mass star-forming regions, but due to both observational and theoretical challenges, our understanding of their chemical evolution is much less clear than that ...
Francesco Fontani, Francesco Fontani, Francesco Fontani, Maria Teresa Beltrán, Anton Vasyunin   +4 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Can Clump Properties Determine Core Distribution in Star Formation? A Statistical Analysis of Magnetohydrodynamic Simulations

The Astrophysical Journal
Dense cores, the progenitors of stars, are in sub-pc scale and fragmented from pc-scale clumps. However, it is still unclear how strongly the fragmentation process is affected by the properties of the host clumps and how these properties influence the ...
Wei-An Chen, S. D. Clarke, Ya-Wen Tang
doaj   +1 more source