Results 91 to 100 of about 288,104 (243)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Global and Local Infall in the ASHES Sample (GLASHES). I. Pilot Study in G337.541

The Astrophysical Journal
Recent high-angular-resolution observations indicate the need for core growth to form high-mass stars. To understand the gas dynamics at the core scale in the very early evolutionary stages before being severely affected by feedback, we have conducted ...
Kaho Morii, Patricio Sanhueza, Timea Csengeri, Fumitaka Nakamura, Sylvain Bontemps, Guido Garay, Qizhou Zhang   +6 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Tracking Star-forming Cores as Mass Reservoirs in Clustered and Isolated Regions Using Numerical Passive Tracer Particles

The Astrophysical Journal
Understanding the physical properties of star-forming cores as mass reservoirs for protostars and the impact of turbulence is crucial in star formation studies.
Shingo Nozaki, Hajime Fukushima, Kazuki Tokuda, Masahiro N. Machida   +3 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

The Milky Way Project: Bridging Intermediate- and High-mass Star Formation with the MIRION Catalog of Yellowballs

The Astrophysical Journal
We describe the construction and use of the Mid-InfraRed Interstellar Objects and Nebulae (MIRION) catalog, which was compiled from 6176 objects identified as “yellowballs” (YBs) by participants in the Milky Way Project.
Kathryn Devine, Grace Wolf-Chase, C. R. Kerton, Nicholas Larose, Maya Coleman, Makenzie Stapley, Ethan Bassingthwaite, Bezawit Mekasha Kassaye, Hritik Rawat, Tharindu Jayasinghe   +9 more
doaj   +1 more source

The star-forming region in Cepheus A

The Astrophysical Journal, 1984
Resultats d'observations de Cep A a 2,1 cm et 6 cm. La condensation contient deux chapelets de regions H II d'environ 0,1 pc de longueur, produites par environ 14 etoiles ressemblant aux etoiles B3 de la sequence principale. Les regions H II sont tres jeunes, ∼10 3 ans et on suggere que l'environnement est controle par un champ ...
Hughes, V.A., Wouterloot, J.G.A.
openaire   +3 more sources

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Dense Cores in IRDC G14.225-0.506 Revealed by ALMA Observations

The Astrophysical Journal
Dense cores in massive, parsec-scale molecular clumps are sites that harbor protocluster formation. We present results from observations toward a hub–filament structure of a massive infrared (IR) dark cloud G14.225-0.506 using the Atacama Large ...
Yanhanle Zhao, Qizhou Zhang, Junhao Liu, Xing Pan, Lingzhen Zeng   +4 more
doaj   +1 more source

The Star Forming Regions of Orion [PDF]

International Astronomical Union Colloquium, 1995
AbstractThe distribution of emission line stars in Orion is presented, based on our recent surveys and other previous ones. Particular attention is given for the central 10 × 10 square degrees to compare some properties of emission line stars and OB association stars. As a result, a possibility of bimodal star formation is suggested in this region.
openaire   +1 more source