Results 91 to 100 of about 47,546 (266)
Star Forming Regions in Cepheus
104 pages, 25 tables, 35 figures; A chapter in the "Handbook of Star Forming Regions, Vol 1: The Northern Sky," ed. Bo Reipurth; ASP Monograph Series. Full resolution version can be found at http://www.konkoly.hu/staff/kun/handbook_chapters/
Kun, M., Kiss, Z. T., Balog, Z.
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Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Different Influence of Gas Accretion on the Evolution of Star-forming and Non-star-forming Galaxies
Using integral field spectroscopic data from the Mapping Nearby Galaxies at Apache Point Observatory survey, we investigate the spatially resolved properties and empirical relations of a star-forming galaxy and a non-star-forming galaxy hosting ...
Min Bao, Wenlong Zhao, Qirong Yuan
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
The Impact of External Radiation on the Inner Disk Chemistry of Planet Formation
The vast majority of young stars hosting planet-forming disks exist within clustered environments, like the Orion Nebula, implying that seemingly “extreme” UV environments (10 ^4 G _0 and above) are not so atypical in the context of planet formation ...
Jenny K. Calahan +2 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Star Forming Regions in Cassiopeia
This chapter describes the Galactic star forming regions in the constellation Cassiopeia, in the Galactic coordinate range 120 deg < l < 130 deg, -5 deg < b < +15 deg. At b > 10 deg the nearby clouds L1333 and L1340 are found in this region.
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