Results 71 to 80 of about 56,054 (306)

CO observations of massive star forming regions at different evolutionary phases

open access: yes, 2006
The (CO)-C-12 (J=1-0), (CO)-C-13 (J=1-0) and (CO)-O-18 (J=1-0) emissions in 9 massive star forming regions, which are believed to be at different stages of massive star formation, were mapped with the 13.7 m millimeter wave telescope at Qinghai Station ...
Xu Ye   +3 more
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Search for compact extragalactic radio sources near massive star-forming regions

open access: yes, 2006
We have used the Very Large Array to search for compact milliarcsecond- size radio sources near methanol masers in high-mass star-forming regions. Such sources are required for very long baseline Interferometry phase-referencing observations.
Reid, M. J.   +3 more
core  

Structure and Dynamics of the Young Massive Star Cluster Westerlund 1

open access: yesThe Astrophysical Journal
We present a structural and dynamical analysis of the young massive star cluster Westerlund 1 (Wd1). Using multiepoch Hubble Space Telescope observations, we measure the proper motions of 10,346 stars and present an unprecedented determination of cluster
Lingfeng Wei   +10 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

A JWST NIRCam/MIRI View of the W51A High-mass Star-forming Region

open access: yesThe Astronomical Journal
We present observations of the W51A region, including the massive protoclusters W51-E and W51-IRS2, with JWST in 10 NIRCam and 5 MIRI filters. In this work, we highlight the most novel features apparent in these images and compare them with other ...
Taehwa Yoo   +12 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Global and Local Infall in the ASHES Sample (GLASHES). I. Pilot Study in G337.541

open access: yesThe Astrophysical Journal
Recent high-angular-resolution observations indicate the need for core growth to form high-mass stars. To understand the gas dynamics at the core scale in the very early evolutionary stages before being severely affected by feedback, we have conducted ...
Kaho Morii   +6 more
doaj   +1 more source

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