Results 71 to 80 of about 3,871,291 (295)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Search for compact extragalactic radio sources near massive star-forming regions

open access: yes, 2006
We have used the Very Large Array to search for compact milliarcsecond- size radio sources near methanol masers in high-mass star-forming regions. Such sources are required for very long baseline Interferometry phase-referencing observations.
Reid, M. J.   +3 more
core  

Multiple Generation Star Formation in Cepheus Flare

open access: yesThe Astronomical Journal
We present an analysis of the young stellar moving group ASCC 127 using Gaia DR3 data, significantly expanding its membership to 3971 stars—double the number identified in previous studies.
Fan Wang   +10 more
doaj   +1 more source

The Star Forming Regions of Orion [PDF]

open access: yesInternational Astronomical Union Colloquium, 1995
AbstractThe distribution of emission line stars in Orion is presented, based on our recent surveys and other previous ones. Particular attention is given for the central 10 × 10 square degrees to compare some properties of emission line stars and OB association stars. As a result, a possibility of bimodal star formation is suggested in this region.
openaire   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Quantifying kinematic substructure in star-forming regions with statistical tests of spatial autocorrelation.

open access: yes, 2021
Poster discussing the application of statistical measures of spatial autocorrelation to studying kinematic structure in star forming ...
Arnold, Becky, Wright, Nicholas
core   +1 more source

The ALMA-QUARKS Survey: Fibers’ Role in Star Formation Unveiled in an Intermediate-mass Protocluster Region of the Vela D Cloud

open access: yesThe Astrophysical Journal
In this paper, we present a detailed analysis of the IRS 17 filament within the intermediate-mass protocluster IRAS 08448-4343 (of ∼10 ^3 L _⊙ ), using ALMA data from the ATOMS 3 mm and QUARKS 1.3 mm surveys.
Dongting Yang   +34 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Solid-state astrochemistry in star-forming regions

open access: yes, 2003
Surface-catalysed chemical reactions, the molecules they form, and the implications for star formation were key themes in an international workshop on “Solid-state chemistry in star-forming regions” at the Lorentz Centre, Leiden University, the ...
Richards, Anita   +4 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

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