Results 71 to 80 of about 288,104 (243)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Direct Observational Evidence of Multi-epoch Massive Star Formation in G24.47+0.49

The Astrophysical Journal Letters
Using new continuum and molecular line data from the Atacama Large Millimeter/submillimeter Array Three-millimeter Observations of Massive Star-forming Regions (ATOMS) survey and archival Very Large Array, 4.86 GHz data, we present direct observational ...
Anindya Saha, Anandmayee Tej, Hong-Li Liu, Tie Liu, Guido Garay, Paul F. Goldsmith, Chang Won Lee, Jinhua He, Mika Juvela, Leonardo Bronfman, Tapas Baug, Enrique Vázquez-Semadeni, Patricio Sanhueza, Shanghuo Li, James O. Chibueze, N. K. Bhadari, Lokesh K. Dewangan, Swagat Ranjan Das, Feng-Wei Xu, Namitha Issac, Jihye Hwang, L. Viktor Tóth   +21 more
doaj   +1 more source

Projection effects in star-forming regions

Astronomy & Astrophysics
Stars are formed as molecular clouds fragment into networks of dense cores, filaments, and sub-clusters. The characteristic spacing of these dense cores is therefore a key observable imprint of the underlying fragmentation physics and is often compared ...
Barnes A. T., Morii K., Pineda J. E., Parker R. J., Schisano E., Traficante A., Redaelli E., Immer K., Henshaw J. D., Sanhueza P., Motte F., Hacar A.   +11 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Multiple Generation Star Formation in Cepheus Flare

The Astronomical Journal
We present an analysis of the young stellar moving group ASCC 127 using Gaia DR3 data, significantly expanding its membership to 3971 stars—double the number identified in previous studies.
Fan Wang, Min Fang, Xiaoting Fu, Yang Su, Xuepeng Chen, Shiyu Zhang, Penghui Liu, Xiao-Long Wang, Haijun Tian, Wenyuan Cui, Zhongmu Li   +10 more
doaj   +1 more source

Locating Star-Forming Regions in Quasar Host Galaxies

, 2013
We present a study of the morphology and intensity of star formation in the host galaxies of eight Palomar-Green quasars using observations with the Hubble Space Telescope.
Ciardullo, R., Eracleous, M., Gronwall, C., Lutz, Dieter, Netzer, H., Shemmer, O., Sturm, Eckhard, Young, J. E.   +7 more
core   +2 more sources

Chemical Processes in Star Forming Regions [PDF]

, 2008
This paper will review the basic concepts of gas-phase and grain surface chemistry of dense molecular clouds, where low mass and high mass stars form. The chemistry of cold pre-stellar cloud cores, where molecular freeze-out and deuterium fractionation dominate, will be presented.
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The ALMA-QUARKS Survey: Fibers’ Role in Star Formation Unveiled in an Intermediate-mass Protocluster Region of the Vela D Cloud

The Astrophysical Journal
In this paper, we present a detailed analysis of the IRS 17 filament within the intermediate-mass protocluster IRAS 08448-4343 (of ∼10 ^3 L _⊙ ), using ALMA data from the ATOMS 3 mm and QUARKS 1.3 mm surveys.
Dongting Yang, Hong-Li Liu, Tie Liu, Anandmayee Tej, Xunchuan Liu, Jinhua He, Guido Garay, Amelia Stutz, Lei Zhu, Sheng-Li Qin, Fengwei Xu, Pak-Shing Li, Mika Juvela, Pablo García, Paul F. Goldsmith, Siju Zhang, Xindi Tang, Patricio Sanhueza, Shanghuo Li, Chang Won Lee, Swagat Ranjan Das, Wenyu Jiao, Xiaofeng Mai, Prasanta Gorai, Yichen Zhang, Zhiyuan Ren, L. Viktor Tóth, Jihye Hwang, Leonardo Bronfman, Ken’ichi Tatematsu, Lokesh Dewangan, James O. Chibueze, Suinan Zhang, Gang Wu, Jinjin Xie   +34 more
doaj   +1 more source