Results 81 to 90 of about 288,104 (243)
Probing Individual Star Forming Regions Within Strongly Lensed Galaxies at z > 1
, 2014 Star formation occurs on physical scales corresponding to individual star forming regions, typically of order ~100 parsecs in size, but current observational facilities cannot resolve these scales within field galaxies beyond the local universe. However,
Bayliss, Matthew B. +4 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Abundances of hydrogen sulfide in star-forming regions
The Astrophysical Journal, 1991 The published version is located at http://adsabs.harvard.edu/full/1991ApJ...366 ...
MINH, YC +3 more
openaire +3 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Structure and Dynamics of the Young Massive Star Cluster Westerlund 1
The Astrophysical JournalWe present a structural and dynamical analysis of the young massive star cluster Westerlund 1 (Wd1). Using multiepoch Hubble Space Telescope observations, we measure the proper motions of 10,346 stars and present an unprecedented determination of cluster
Lingfeng Wei +10 more
doaj +1 more source
VLA and ATCA Search for Natal Star Clusters in Nearby Star-Forming Galaxies
, 2011 In order to investigate the relationship between the local environment and the properties of natal star clusters, we obtained radio observations of 25 star-forming galaxies within 20 Mpc using the Very Large Array (VLA) and the Australia Telescope ...
Aversa, Alan +4 more
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
A JWST NIRCam/MIRI View of the W51A High-mass Star-forming Region
The Astronomical JournalWe present observations of the W51A region, including the massive protoclusters W51-E and W51-IRS2, with JWST in 10 NIRCam and 5 MIRI filters. In this work, we highlight the most novel features apparent in these images and compare them with other ...
Taehwa Yoo +12 more
doaj +1 more source