Results 151 to 160 of about 318,054 (345)

The IRAS 08589-4714 star-forming region

, 2016
Fil: Saldaño, Hugo Pablo. Universidad Nacional de Cordoba. Observatorio Astronomico de Cordoba; Argentina.
Saldaño, Hugo Pablo, Vasquez, Javier, Gómez, M., Cappa, Cristina Elisabet, Duronea, Nicolás Urbano, Rubio, M.   +5 more
openaire   +4 more sources

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Probing Turbulence, Gravity, Supernovae, and Magnetic Field Effects with the 6D Kinematics of Young Stars in Milky Way Star-forming Regions

The Astrophysical Journal
The dynamics of star-forming gas can be affected by many physical processes, such as turbulence, gravity, supernova explosions, and magnetic fields. In this paper, we investigate several nearby star-forming regions (Orion, Upper Sco, Taurus, and Perseus)
Benjamin N. Velguth, Yuan Li, Trung Ha, Yue Hu, Marina Kounkel, Siyao Xu, Robert Gutermuth, Hui Li, Martin D. Weinberg   +8 more
doaj   +1 more source

Interferometric Observations of Chemistry in High-Mass Star-Forming Regions [PDF]

, 2000
P. Schilke, K. M. Menten, F. Wyrowski, C. M. Walmsley   +3 more
openalex   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

The Evolution of Substructure during Star Cluster Assembly

The Astrophysical Journal
Star cluster formation and assembly occur inside filamentary and turbulent molecular clouds, which imprint both spatial and kinematic substructure on the young cluster.
Edwin Laverde-Villarreal, Alison Sills, Claude Cournoyer-Cloutier, Veronica Arias Callejas   +3 more
doaj   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source

Planet Formation Regulated by Galactic-scale Interstellar Turbulence

The Astrophysical Journal Letters
Planet formation occurs over a few Myr within protoplanetary disks of dust and gas, which are often assumed to evolve in isolation. However, extended gaseous structures have been uncovered around many protoplanetary disks, suggestive of late-stage infall
Andrew J. Winter, Myriam Benisty, Sean M. Andrews   +2 more
doaj   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

B-fields and Dust in Interstellar Filaments Using Dust Polarization (BALLAD-POL). II. Testing the Radiative Torque Paradigm in Musca and OMC-1

The Astrophysical Journal
Polarization of starlight and thermal dust emission caused by aligned dust grains is a valuable tool to characterize magnetic fields ( B -fields) and constrain dust properties. However, the grain alignment physics is not fully understood.
Nguyen Bich Ngoc, Thiem Hoang, Pham Ngoc Diep, Le Ngoc Tram   +3 more
doaj   +1 more source