Results 41 to 50 of about 41,054 (268)

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

JWST-FEAST: Feedback in Emerging extrAgalactic Star clusTers: Calibration of Star Formation Rates in the Mid-infrared with NGC 628

open access: yesThe Astrophysical Journal
New JWST near-infrared imaging of the nearby galaxy NGC 628 from the JWST Cycle 1 program Feedback in Emerging extrAgalactic Star clusTers (JWST-FEAST) is combined with archival JWST mid-infrared imaging to calibrate the 21 μ m emission as a star ...
Daniela Calzetti   +21 more
doaj   +1 more source

ALMA Survey of Orion Planck Galactic Cold Clumps (ALMASOP): A Forming Quadruple System with Continuum “Ribbons” and Intricate Outflows

open access: yesThe Astrophysical Journal Letters, 2023
One of the most poorly understood aspects of low-mass star formation is how multiple-star systems are formed. Here we present the results of Atacama Large Millimeter/submillimeter Array (ALMA) Band 6 observations toward a forming quadruple protostellar ...
Qiu-yi Luo   +33 more
doaj   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Tracking Star-forming Cores as Mass Reservoirs in Clustered and Isolated Regions Using Numerical Passive Tracer Particles

open access: yesThe Astrophysical Journal
Understanding the physical properties of star-forming cores as mass reservoirs for protostars and the impact of turbulence is crucial in star formation studies.
Shingo Nozaki   +3 more
doaj   +1 more source

Star-forming complexes in the polar ring galaxy NGC660

open access: yesOpen Astronomy, 2017
Galaxies with polar rings consist of two subsystems, a disk and a ring, which rotate almost in orthogonal planes. In this paper, we analyze the parameters characterizing the composition of the interstellar medium and star formation in star-forming ...
Smirnova Ksenia I.   +2 more
doaj   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

Dense Cores in IRDC G14.225-0.506 Revealed by ALMA Observations

open access: yesThe Astrophysical Journal
Dense cores in massive, parsec-scale molecular clumps are sites that harbor protocluster formation. We present results from observations toward a hub–filament structure of a massive infrared (IR) dark cloud G14.225-0.506 using the Atacama Large ...
Yanhanle Zhao   +4 more
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Different Influence of Gas Accretion on the Evolution of Star-forming and Non-star-forming Galaxies

open access: yesThe Astrophysical Journal
Using integral field spectroscopic data from the Mapping Nearby Galaxies at Apache Point Observatory survey, we investigate the spatially resolved properties and empirical relations of a star-forming galaxy and a non-star-forming galaxy hosting ...
Min Bao, Wenlong Zhao, Qirong Yuan
doaj   +1 more source

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