Results 51 to 60 of about 44,874 (266)

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Signatures of Mass Segregation from Competitive Accretion and Monolithic Collapse

open access: yesThe Astrophysical Journal
The two main competing theories proposed to explain the formation of massive (>10 M _⊙ ) stars—competitive accretion and monolithic core collapse—make different observable predictions for the environment of the massive stars during, and immediately after,
Richard J. Parker   +3 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Digging into the Interior of Hot Cores with ALMA (DIHCA). VII. Disk Candidates around High-mass Stars and Evidence of Anisotropic Infall

open access: yesThe Astrophysical Journal
We study the kinematics of condensations in 30 fields forming high-mass stars with the Atacama Large Millimeter/submillimeter Array at a high resolution of $\sim 0\mathop{.}\limits{^{\prime\prime} }08$ on average (∼230 au).
Fernando A. Olguin   +21 more
doaj   +1 more source

Monitoring Water Masers in Star-Forming Regions [PDF]

open access: yesAstrophysics and Space Science, 2005
9 pages, 1 table, 11 figures. Accepted for publ. in Ap&SpSci. Refereed contribution to "Dense Molecular Gas around Protostars and in Galactic Nuclei", European Workshop 2004 on Astronomical Molecules. Eds. Y. Hagiwara, W.A. Baan, H.J.
Brand, J.   +6 more
openaire   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Alignment Parameters: Quantifying Dense Core Alignment in Star-forming Regions

open access: yesThe Astrophysical Journal
Recent high-resolution observations at millimeter (mm) and submillimeter wavelengths reveal a diverse spatial distribution for subparsec-scale dense cores within star-forming regions, ranging from clustered to aligned arrangements.
Wei-An Chen   +3 more
doaj   +1 more source

Exploring Stellar Cluster and Feedback-driven Star Formation in the Galactic Mid-infrared Bubble [HKS2019] E70

open access: yesThe Astrophysical Journal, 2023
We present a comprehensive analysis of the Galactic mid-infrared bubble [HKS2019] E70 (E70) by adopting a multiwavelength approach to understand the physical environment and star formation scenario around it.
Aayushi Verma   +10 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Direct Observational Evidence of Multi-epoch Massive Star Formation in G24.47+0.49

open access: yesThe Astrophysical Journal Letters
Using new continuum and molecular line data from the Atacama Large Millimeter/submillimeter Array Three-millimeter Observations of Massive Star-forming Regions (ATOMS) survey and archival Very Large Array, 4.86 GHz data, we present direct observational ...
Anindya Saha   +21 more
doaj   +1 more source

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