Results 71 to 80 of about 12,031 (214)

Chemical composition and fundamental parameters of roAp stars

, 1998
5 pages, 2 figures (the first being in fact a table), to appear in: Proc. of the 26th workshop of the European Working Group on CP stars, eds. P. North, A. Schnell and J. Ziznovsky, Contrib. Astr. Obs. Skalnate Pleso Vol.
openaire   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Symmetry in fundamental parameters of galaxies on the star-forming main sequence

Monthly Notices of the Royal Astronomical Society
ABSTRACT The Star-Forming Main Sequence (SFMS) serves as a critical framework for understanding galaxy evolution, highlighting the relationship between star formation rates (SFR) and stellar masses $M_*$ across cosmic time, for star forming galaxies.
Zhicheng He, Enci Wang, Luis C Ho, Huiyuan Wang, Yong Shi, Xu Kong, Tinggui Wang   +6 more
openaire   +2 more sources

The Fundamental Stellar Parameters of FGK Stars in the SEEDS Survey

, 2017
Large exoplanet surveys have successfully detected thousands of exoplanets to-date. Utilizing these detections and non-detections to constrain our understanding of the formation and evolution of planetary systems also requires a detailed understanding of the basic properties of their host stars.
Rich, Evan A., Wisniewski, John P., McElwain, Michael W., Hashimoto, Jun, Kudo, Tomoyuki, Kusakabe, Nobuhiko, Okamoto, Yoshiko K., Abe, Lyu, Akiyama, Eiji, Brandner, Wolfgang, Brandt, Timothy D., Cargile, Phillip, Carson, Joseph C., Currie, Thayne M, Egner, Sebastian, Feldt, Markus, Fukagawa, Misato, Goto, Miwa, Grady, Carol A., Guyon, Olivier, Hayano, Yutaka, Hayashi, Masahiko, Hayashi, Saeko S., Hebb, Leslie, Helminiak, Krzysztof G., Henning, Thomas, Hodapp, Klaus W., Ishii, Miki, Iye, Masanori, Janson, Markus, Kandori, Ryo, Knapp, Gillian R., Kuzuhara, Masayuki, Kwon, Jungmi, Matsuo, Taro, Mayama, Satoshi, Miyama, Shoken, Momose, Munetake, Morino, Jun-Ichi, Moro-Martin, Amaya, Nakagawa, Takao, Nishimura, Tetsuo, Oh, Daehyeon, Pyo, Tae-Soo, Schlieder, Joshua, Serabyn, Eugene, Sitko, Michael L., Suenaga, Takuya, Suto, Hiroshi, Suzuki, Ryuji, Takahashi, Yasuhiro H., Takami, Michihiro, Takato, Naruhisa, Terada, Hiroshi, Thalmann, Christian, Tomono, Daigo, Turner, Edwin L., Watanabe, Makoto, Yamada, Toru, Takami, Hideki, Usuda, Tomonori, Tamura, Motohide   +61 more
openaire   +2 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source