Results 81 to 90 of about 11,343 (235)

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

The CARMENES search for exoplanets around M dwarfs -- A deep learning approach to determine fundamental parameters of target stars [PDF]

, 2020
V. M. Passegger, A. Bello-García, Joaquín Ordieres‐Meré, J. A. Caballero, A. Schweitzer, Ana González‐Marcos, I. Ribas, A. Reiners, A. Quirrenbach, P. J. Amado, M. Azzaro, F. F. Bauer, V. J. S. Béjar, M. Cortés‐Contreras, S. Dreizler, A. P. Hatzes, Th. Henning, S. V. Jeffers, A. Kaminski, M. Kürster, M. Lafarga, E. Marfil, D. Montes, J. C. Morales, E. Nagel, L. M. Sarro, E. Solano, H. M. Tabernero, M. Zechmeister   +28 more
openalex   +1 more source

Fundamental parameters of the Ap-stars GO And, 84 UMa, and κ Psc [PDF]

, 2021
A. M. Romanovskaya, D. Shulyak, T. Ryabchikova, T. Sitnova   +3 more
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

FUNDAMENTAL PARAMETERS OF MAIN-SEQUENCE STARS IN AN INSTANT WITH MACHINE LEARNING [PDF]

, 2016
Earl P. Bellinger, George C. Angelou, Saskia Hekker, Sarbani Basu, Warrick H. Ball, Elisabeth Guggenberger   +5 more
openalex   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Towards an Increased Accuracy of Fundamental Properties of Stars: Proposing a Set of Nominal Astrophysical Parameters and Constants [PDF]

, 2011
A. Prša, P. Harmanec
openalex   +1 more source

Fundamental parameters of 8 Am stars: comparing observations with theory

, 2014
In this paper we present a detailed analysis of a sample of eight Am stars, four of them are in the {\it Kepler} field of view. We derive fundamental parameters for all observed stars, effective temperature, gravity, rotational and radial velocities, and chemical abundances by spectral synthesis method.
Catanzaro, G., Ripepi, V.
openaire   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source