Results 21 to 30 of about 736 (218)
Black Holes as Frozen Stars: Regular Interior Geometry
Fortschritte der Physik, 2023 AbstractThe authors have proposed a model geometry for the interior of a regular black hole (BH) mimicker, the frozen star, whose most startling feature is that each spherical shell in its interior is a surface of infinite redshift. The geometry is a solution of the Einstein equations which is sourced by an exotic matter with maximally negative radial ...
Ram Brustein +3 more
openaire +3 more sources
Do hyperons exist in the interior of neutron stars? [PDF]
The European Physical Journal A, 2016 In this work we review the role of hyperons on the properties of neutron and proto-neutron stars. In particular, we revise the so-called "hyperon puzzle", go over some of the solutions proposed to tackle it, and discuss the implications that the recent measurements of unusually high neutron star masses have on our present knowledge of hypernuclear ...
Chatterjee, D., Vidaña, I.
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Pediatric Blood &Cancer, EarlyView.ABSTRACT The medical burdens of sickle cell disease (SCD) and transfusion‐dependent β‐thalassemia (TDT) are chronic and cumulative, even in children. Yet the effects expand beyond medications and healthcare visits due to their impacts on school attendance, academic performance, and peer engagement.
Mary Ann Etling +2 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Improved analytic modeling of neutron star interiors [PDF]
Physical Review D, 2019 Studies of neutron stars are extremely timely given the recent detection of gravitational waves from a binary neutron star merger GW170817, and an International Space Station payload NICER currently in operation that aims to determine radii of neutron stars to a precision better than 5%. In many cases, neutron star solutions are constructed numerically
Jiang, Nan, Yagi, Kent
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source