Results 31 to 40 of about 9,999 (218)
Rotational Velocities of B Stars
We measured the projected rotational velocities of 1092 northern B stars listed in the Bright Star Catalogue (BSC) and calibrated them against the 1975 Slettebak et al. system. We found that the published values of B dwarfs in the BSC average 27% higher than those standards.
Abt, Helmut A. +2 more
openaire +2 more sources
From an Intermittent Rotating Star to a Leader [PDF]
Considering an asynchronous system made up of n processes and where up to t of them can crash, finding the weakest assumptions that such a system has to satisfy for a common leader to be eventually elected is one of the holy grail quests of fault-tolerant asynchronous computing. This paper is a step in such a quest. It has two main contributions. First,
Fernández, Antonio, Raynal, Michel
openaire +2 more sources
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Rotation: a fundamental parameter of massive stars [PDF]
Massive stars are rapid rotators. Equatorial rotation velocities span the range vrot = 100–400 km s−1, with B stars rotating closest to their break-up speed vcrit (Howarth et al. 1997). During the last decade, many observations have revealed unusual surface abundances that may require additional internal mixing (beyond that of simple convection and ...
Langer, Norbert (Prof. Dr.) +2 more
openaire +2 more sources
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Rotation Mixing and Variability in a Stars [PDF]
The purpose of this paper is to contribute to answer the question : why among A stars are there variable and “constant” stars? To do this we will first review the observational properties of these stars, then discuss the theoretical models based on the interplay between microscopic diffusion and rotation, and finally discuss the “unsolved” questions !
openaire +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source

