Results 111 to 120 of about 1,877,657 (298)

Development of statistical framework to evaluate the features of innovative start-ups in Ukraine

open access: yesСтатистика України, 2016
Governments of the leading countries, recognized that start-ups (from the English "start-up" - start) are the engines of innovative development of economy and making efforts, on the one hand, to create these basic conditions; on the other - to implement ...
O. B. Salikhova, O. O. Kurchenko
doaj  

ENTREPRENEURIAL SELLING: CHALLENGES OF AN ENTREPRENEUR WHO WANTED TO SAVE LIVES

open access: yesAdministração: Ensino e Pesquisa
This case portrays the real challenges faced by Dr. Paulino Souza Neto, a vascular surgeon, radiologist, and inventor of technologies in the healthcare sector aimed at patient safety.
Renato Fernandes
doaj   +1 more source

Regional Path-Dependence in Start-up Activity [PDF]

open access: yes
This paper studies the impact of an existing industrial structure in a region on the number of start-ups in this region. The aim is to detect path-dependencies in the regional industry structure. To this end we study empirically the regional factors that
Dirk Fornahl, Thomas Brenner
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Experimental investigation of hydrogen production performance of PEM electrolyze

open access: yesScientific Reports
As global awareness of environmental protection increases, hydrogen is seen as a promising solution due to its high energy density and zero-emission combustion. The PEM electrolyze combined with renewable energy power generation is an effective method to
Chen Aijun   +4 more
doaj   +1 more source

R&D financing of start-up firms : How much does founders' human capital matter? [PDF]

open access: yes
This paper explores research and development (R&D) financing of start-up firms. Using a sample from an original survey conducted in 2008, we identify whether initial funds and founder-specific characteristics relate to R&D investment of start-up firms in
Honjo, Yuji   +2 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Developing an Entrepreneurial Ecosystem Framework for Student-Led Start-Ups in Higher Education

open access: yesEducation Sciences
Higher education institutions (HEIs) are increasingly seen as central actors in entrepreneurial ecosystems, yet their support mechanisms do not always align with the needs of student entrepreneurs.
Artūras Jurgelevičius   +3 more
doaj   +1 more source

The Gender Gap in Start-up Funding: The Role of Investors\u27 Benevolent Sexism [PDF]

open access: yes, 2019
Past research has consistently shown that female-led ventures tend to receive less funding than male-led ventures, but the reasons for this gap are unclear.
Nguyen, Nhu
core   +1 more source

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