Results 41 to 50 of about 1,242,659 (298)

A multifunctional dynamic voltage restorer for power quality improvement [PDF]

, 2018
Power quality is a major concern in electrical power systems. The power quality disturbances such as sags, swells, harmonic distortion and other interruptions have an impact on the electrical devices and machines and in severe cases can cause serious ...
Dung, Vo Tien, Goňo, Radomír, Leonowicz, Zbigniew   +2 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

A One-Dimensional Effective Model for Nanotransistors in Landauer–Büttiker Formalism

Micromachines, 2020
In a series of publications, we developed a compact model for nanotransistors in which quantum transport in a variety of industrial nano-FETs was described quantitatively.
Ulrich Wulf
doaj   +1 more source

How to Start a Biomedical Device Company

JACC: Basic to Translational Science, 2017
Summary: Taking a solution for a clinical unmet need from a mere idea to a profitable medical device company is a long and complex process. After developing a prototype solution, the physician-inventor must quickly file a patent to protect his or her intellectual property.
J. Michael DiMaio, MD, Brittany A. Potz, MD, Jeffrey E. Thatcher, PhD, John J. Squiers, MD   +3 more
openaire   +2 more sources

Self-starting circuit for switching regulators [PDF]

, 1969
Schematic is provided on a self-starting circuit for a switching regulator which uses a logic circuit to sense a change in output voltage and provides a correction signal for dc power sources.
Schraut, E. H., Sohl, G.
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Стартер-генератор на борті рухливих установок

Elektrotehnìka ta Elektroenergetika, 2012
Робота присвячена розв’язку питання створення одномашинної електричної мережі на борті рухливих установок. Дано поняття про конструктивні особливості нової системи стартер-генератора, проаналізовані режими стартера й генератора, надана силова електрична ...
S. A. Khanakhmedova
doaj   +1 more source

A Kind of Regenerable Optical Fiber Cold Connection Device in Coal Mine

Meikuang Anquan, 2020
In view of the poor underground environment of coal mines, the difficulties in fiber welding, and the safety accidents caused by sparks generated by hot fused fiber at high temperature, a renewable fiber cold connection device was developed. Through the
ZHANG Jinhao, CHEN Min
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Single-layer metallicity and interface magnetism of epitaxial graphene on SiC(000$\bar{1}$)

, 2011
We perform density functional theory calculations for the determination of the structural and electronic properties of epitaxial graphene on 4H-SiC(000$\bar{1}$). Using commensurate supercells that minimize non-physical stresses we show that, in contrast
Deretzis, I., La Magna, A.
core   +1 more source