The effects of auditory startle and nonstartle stimuli on step initiation in Parkinson's disease [PDF]
Movement Disorders, 2012 AbstractBackground:Auditory external cues enhance step initiation in Parkinson's disease (PD) patients. We wanted to explore whether a startle reaction has a comparable effect on step initiation in PD.Methods:Thirteen PD patients and 13 aged‐matched controls participated in this study.
Fernández del Olmo, Miguel +5 more
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Startle Disease: An Overlooked Symptom of CTNNB1-Related Neurodevelopmental Disorder With Spastic Diplegia and Visual Defects. [PDF]
Neurol Genet, 2022 BACKGROUND AND OBJECTIVES: Neurodevelopmental disorder with spastic diplegia and visual defect (NEDSDV) is a recently described rare syndrome caused by loss-of-function variations in CTNNB1 gene which includes developmental delay, intellectual deficiency,
Bulot V +3 more
europepmc +2 more sources
Dual Role of Dysfunctional Asc-1 Transporter in Distinct Human Pathologies, Human Startle Disease, and Developmental Delay. [PDF]
eNeuro, 2023 Human startle disease is associated with mutations in distinct genes encoding glycine receptors, transporters or interacting proteins at glycinergic synapses in spinal cord and brainstem. However, a significant number of diagnosed patients does not carry
Drehmann P +7 more
europepmc +2 more sources
Frontiers in Neurology, 2020 Here, we report the case of a 63-year-old woman affected by abnormal, excessive, and involuntary reactions to harmless and unexpected sensory stimuli, compatible with the diagnosis of hyperekplexia.
Annibale Antonioni +2 more
doaj +1 more source
Anaesthetic Implications of Hyperekplexia—'Startle Disease’ [PDF]
Anaesthesia and Intensive Care, 2008 This report describes anaesthesia for consanguineous siblings with the rare genetic condition hyperekplexia. This condition is also known as ‘stiff baby syndrome’ or ‘startle disease’. Hyperekplexia can present in major and minor forms and is caused by a mutation in chromosome 5 which results in a defect in the α-1 subunit of the inhibitory glycine ...
R, Garg, R, Ramachandran, P, Sharma
openaire +2 more sources
Aversiveness of sound in marine mammals : psycho-physiological basis, behavioural correlates and potential applications [PDF]
, 2010 Understanding what psycho-physiological and behavioural factors influence aversiveness of sound in marine mammals is important for conservation and practical applications.
Götz, Thomas
core +2 more sources
Repeated elicitation of the acoustic startle reflex leads to sensitisation in subsequent avoidance behaviour and induces fear conditioning [PDF]
, 2011 Background: Autonomous reflexes enable animals to respond quickly to potential threats, prevent injury and mediate fight or flight responses. Intense acoustic stimuli with sudden onsets elicit a startle reflex while stimuli of similar intensity but with ...
Vincent M Janik +5 more
core +1 more source
Anxiety and Startle Phenotypes in Glrb Spastic and Glra1 Spasmodic Mouse Mutants
Frontiers in Molecular Neuroscience, 2020 A GWAS study recently demonstrated single nucleotide polymorphisms (SNPs) in the human GLRB gene of individuals with a prevalence for agoraphobia. GLRB encodes the glycine receptor (GlyRs) β subunit.
Natascha Schaefer +8 more
doaj +1 more source
, 2023 <p>We have re-implemented our stochastic search algorithm <code>startle</code> in modern C++ and substantially improved the performance of the procedure.</p ...
Palash Sashittal, Henri Schmidt
core +1 more source
Moyamoya disease with exaggerated startle response: A rare co-occurrence
Annals of Indian Academy of Neurology, 2013 Rajendra Singh Jain +3 more
doaj +3 more sources