Results 31 to 40 of about 1,741,412 (341)
Role of JAK/STAT in the Neuroinflammation and its Association with Neurological Disorders
Background: Innate immunity is mediated by a variety of cell types, including microglia, macrophages, and neutrophils, and serves as the immune system's first line of defense.
M. Jain +6 more
semanticscholar +1 more source
Anaphylaxis is a severe, potentially life-threatening acute allergic reaction that involves more than one system of the body.
openaire +3 more sources
The authors generalize the dynamical system constructed by J. Auslander in 1959, resulting in perhaps the simplest family of examples of minimal but not strictly ergodic systems. A characterization of unique ergodicity and mean-L-stability is given.
Haddad, K. N., Johnson, Aimee S. A.
core +2 more sources
Pancreatic ductal adenocarcinoma (PDAC) is poorly responsive to therapies and histologically contains a paucity of neoplastic cells embedded within a dense desmoplastic stroma. Within the stroma, cancer-associated fibroblasts (CAF) secrete tropic factors
Giulia Biffi +7 more
semanticscholar +1 more source
The potential roles of JAK/STAT signaling in the progression of osteoarthritis
Osteoarthritis (OA) is an age-related chronic progressive degenerative disease that induces persistent pain and disabilities. The development of OA is a complex process, and the risk factors are various, including aging, genetics, trauma and altered ...
Qingluo Zhou +8 more
semanticscholar +1 more source
Quercetin as a JAK–STAT inhibitor: a potential role in solid tumors and neurodegenerative diseases
The Janus kinase–signal transducer and activator of transcription (JAK–STAT) pathway is involved in many immunological processes, including cell growth, proliferation, differentiation, apoptosis, and inflammatory responses.
Hamidreza Zalpoor +7 more
semanticscholar +1 more source
În articol sunt prezentate rezultatele studiului algoflorei lacului „La Izvor”, în care au fost evidenţiate 198 de specii şi varietăţi de alge, majoritatea fiind forme bentonice caracteristice epipelonului, epipsamonului, epilitonului şi epifitonului ...
Lilia Brînză +5 more
doaj +1 more source
Inflammation contributes centrally to cardiovascular diseases, and anti-inflammatory treatments can reduce cardiovascular events. The JAK-STAT pathway is an emerging target in inflammation, mainly in rheumatoid arthritis (RA) and chronic ...
C. Baldini +4 more
semanticscholar +1 more source
JAK-STAT Signaling: A Double-Edged Sword of Immune Regulation and Cancer Progression
Janus kinase-signal transducer and activator of transcription (JAK-STAT) signaling mediates almost all immune regulatory processes, including those that are involved in tumor cell recognition and tumor-driven immune escape. Antitumor immune responses are
Katie L. Owen +2 more
semanticscholar +1 more source
Neutrophils play a crucial role in the innate immune response as a first line of defense in many diseases, including cancer. Tumor-associated neutrophils (TANs) can either promote or inhibit tumor growth in various steps of cancer progression via mutual ...
Donggu Lee +3 more
doaj +1 more source

